(5-Chloro-2-hydroxyphenyl)-(4-methylpiperazin-1-yl)methanone
TL;DR: (5-Chloro-2-hydroxyphenyl)-(4-methylpiperazin-1-yl)methanone (CAS 37133-61-2) is a chemical compound with molecular formula C12H15ClN2O2 and molecular weight 254.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5-chloro-2-hydroxyphenyl)-(4-methylpiperazin-1-yl)methanone
Also Known As: 4-(5-chlorosalicyloyl)-1-methylpiperazine, (5-chloro-2-hydroxy-phenyl)-(4-methylpiperazin-1-yl)methanone, (5-chloro-2-hydroxyphenyl)-(4-methylpiperazin-1-yl)methanone
| Molecular Formula | C12H15ClN2O2 |
|---|---|
| Molecular Weight | 254.08 g/mol |
| LogP | 1.4332 |
| Topological Polar Surface Area | 43.78 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 254.0822 |
| Heavy Atoms | 17 |
| Complexity | 428.51385 |
Chemical Identifiers
| CAS Number | 37133-61-2 |
|---|---|
| SMILES | CN1CCN(CC1)C(=O)C2=C(C=CC(=C2)Cl)O |
Product Overview
(5-Chloro-2-hydroxyphenyl)-(4-methylpiperazin-1-yl)methanone (CAS 37133-61-2), with molecular formula C12H15ClN2O2 and molecular weight 254.08 g/mol. IUPAC: (5-chloro-2-hydroxyphenyl)-(4-methylpiperazin-1-yl)methanone.
Chemical Property Profile of (5-Chloro-2-hydroxyphenyl)-(4-methylpiperazin-1-yl)methanone
Property Insights of (5-Chloro-2-hydroxyphenyl)-(4-methylpiperazin-1-yl)methanone
The XLogP value of 1.4332 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (5-Chloro-2-hydroxyphenyl)-(4-methylpiperazin-1-yl)methanone. With a topological polar surface area (TPSA) of 43.78 Ų, (5-Chloro-2-hydroxyphenyl)-(4-methylpiperazin-1-yl)methanone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (5-Chloro-2-hydroxyphenyl)-(4-methylpiperazin-1-yl)methanone has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (5-Chloro-2-hydroxyphenyl)-(4-methylpiperazin-1-yl)methanone?
The CAS number of (5-Chloro-2-hydroxyphenyl)-(4-methylpiperazin-1-yl)methanone is 37133-61-2.
What is the molecular formula of (5-Chloro-2-hydroxyphenyl)-(4-methylpiperazin-1-yl)methanone?
The molecular formula of (5-Chloro-2-hydroxyphenyl)-(4-methylpiperazin-1-yl)methanone is C12H15ClN2O2.
What is the molecular weight of (5-Chloro-2-hydroxyphenyl)-(4-methylpiperazin-1-yl)methanone?
The molecular weight of (5-Chloro-2-hydroxyphenyl)-(4-methylpiperazin-1-yl)methanone is 254.08 g/mol.
Where can I buy (5-Chloro-2-hydroxyphenyl)-(4-methylpiperazin-1-yl)methanone?
You can request a quote for (5-Chloro-2-hydroxyphenyl)-(4-methylpiperazin-1-yl)methanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (5-Chloro-2-hydroxyphenyl)-(4-methylpiperazin-1-yl)methanone?
Yes, KEHONG BIO provides custom synthesis services for (5-Chloro-2-hydroxyphenyl)-(4-methylpiperazin-1-yl)methanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.