AF-399/40771646
TL;DR: AF-399/40771646 (CAS 371235-59-5) is a chemical compound with molecular formula C21H18N2O4S and molecular weight 394.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(2-hydroxyphenyl)-2-[(5Z)-5-[(E)-2-methyl-3-phenylprop-2-enylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide
Also Known As: AF-399/40771646, N-(2-hydroxyphenyl)-2-{(5Z)-5-[(2E)-2-methyl-3-phenylprop-2-en-1-ylidene]-2,4-dioxo-1,3-thiazolidin-3-yl}acetamide, N-(2-hydroxyphenyl)-2-[5-(2-methyl-3-phenyl-2-propen-1-ylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide, 2-[5-((2E)-2-methyl-3-phenylprop-2-enylidene)-2,4-dioxo(1,3-thiazolidin-3-yl)] -N-(2-hydroxyphenyl)acetamide, N-(2-hydroxyphenyl)-2-((Z)-5-((E)-2-methyl-3-phenylallylidene)-2,4-dioxothiazolidin-3-yl)acetamide
| Molecular Formula | C21H18N2O4S |
|---|---|
| Molecular Weight | 394.10 g/mol |
| LogP | 4.0135 |
| Topological Polar Surface Area | 86.71 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 394.09872 |
| Heavy Atoms | 28 |
| Complexity | 982.9099 |
Chemical Identifiers
| CAS Number | 371235-59-5 |
|---|---|
| SMILES | C/C(=C\C1=CC=CC=C1)/C=C\2/C(=O)N(C(=O)S2)CC(=O)NC3=CC=CC=C3O |
Product Overview
AF-399/40771646 (CAS 371235-59-5), with molecular formula C21H18N2O4S and molecular weight 394.10 g/mol. IUPAC: N-(2-hydroxyphenyl)-2-[(5Z)-5-[(E)-2-methyl-3-phenylprop-2-enylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide.
Chemical Property Profile of AF-399/40771646
Property Insights of AF-399/40771646
The XLogP value of 4.0135 indicates that AF-399/40771646 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 86.71 Ų falls within the moderate polarity range, balancing permeability and solubility for AF-399/40771646. Following Lipinski's Rule of Five, AF-399/40771646 has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AF-399/40771646?
The CAS number of AF-399/40771646 is 371235-59-5.
What is the molecular formula of AF-399/40771646?
The molecular formula of AF-399/40771646 is C21H18N2O4S.
What is the molecular weight of AF-399/40771646?
The molecular weight of AF-399/40771646 is 394.10 g/mol.
Where can I buy AF-399/40771646?
You can request a quote for AF-399/40771646 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AF-399/40771646?
Yes, KEHONG BIO provides custom synthesis services for AF-399/40771646 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.