2-(4-(6-nitro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-((3-nitrophenyl)amino)acrylonitrile structure

2-(4-(6-nitro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-((3-nitrophenyl)amino)acrylonitrile

TL;DR: 2-(4-(6-nitro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-((3-nitrophenyl)amino)acrylonitrile (CAS 371223-96-0) is a chemical compound with molecular formula C21H11N5O6S and molecular weight 461.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

3-(3-nitroanilino)-2-[4-(6-nitro-2-oxochromen-3-yl)-1,3-thiazol-2-yl]prop-2-enenitrile

Also Known As: 2-(4-(6-nitro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-((3-nitrophenyl)amino)acrylonitrile, 3-(3-nitroanilino)-2-[4-(6-nitro-2-oxochromen-3-yl)-1,3-thiazol-2-yl]prop-2-enenitrile, 2-[4-(6-nitro-2-oxo-chromen-3-yl)-1,3-thiazol-2-yl]-3-[(3-nitrophenyl)amino]prop-2-enenitrile

CAS: 371223-96-0
Molecular Formula C21H11N5O6S
Molecular Weight 461.04 g/mol
LogP 4.70948
Topological Polar Surface Area 165.2 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 10
Rotatable Bonds 6
Exact Mass 461.043
Heavy Atoms 33
Complexity 1548.7792

Chemical Identifiers

CAS Number 371223-96-0
SMILES C1=CC(=CC(=C1)[N+](=O)[O-])NC=C(C#N)C2=NC(=CS2)C3=CC4=C(C=CC(=C4)[N+](=O)[O-])OC3=O

Product Overview

2-(4-(6-nitro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-((3-nitrophenyl)amino)acrylonitrile (CAS 371223-96-0), with molecular formula C21H11N5O6S and molecular weight 461.04 g/mol. IUPAC: 3-(3-nitroanilino)-2-[4-(6-nitro-2-oxochromen-3-yl)-1,3-thiazol-2-yl]prop-2-enenitrile.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 2-(4-(6-nitro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-((3-nitrophenyl)amino)acrylonitrile

XLogP
4.70948
TPSA (Topological Polar Surface Area)
165.2
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
10
Rotatable Bonds
6
Heavy Atoms
33
Complexity
1548.7792
Exact Mass
461.043
Monoisotopic Mass
461.043
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2-(4-(6-nitro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-((3-nitrophenyl)amino)acrylonitrile

The XLogP value of 4.70948 indicates that 2-(4-(6-nitro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-((3-nitrophenyl)amino)acrylonitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 165.2 Ų indicates high polarity, suggesting 2-(4-(6-nitro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-((3-nitrophenyl)amino)acrylonitrile may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 2-(4-(6-nitro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-((3-nitrophenyl)amino)acrylonitrile has 1 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2-(4-(6-nitro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-((3-nitrophenyl)amino)acrylonitrile?

The CAS number of 2-(4-(6-nitro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-((3-nitrophenyl)amino)acrylonitrile is 371223-96-0.

What is the molecular formula of 2-(4-(6-nitro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-((3-nitrophenyl)amino)acrylonitrile?

The molecular formula of 2-(4-(6-nitro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-((3-nitrophenyl)amino)acrylonitrile is C21H11N5O6S.

What is the molecular weight of 2-(4-(6-nitro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-((3-nitrophenyl)amino)acrylonitrile?

The molecular weight of 2-(4-(6-nitro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-((3-nitrophenyl)amino)acrylonitrile is 461.04 g/mol.

Where can I buy 2-(4-(6-nitro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-((3-nitrophenyl)amino)acrylonitrile?

You can request a quote for 2-(4-(6-nitro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-((3-nitrophenyl)amino)acrylonitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2-(4-(6-nitro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-((3-nitrophenyl)amino)acrylonitrile?

Yes, KEHONG BIO provides custom synthesis services for 2-(4-(6-nitro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-((3-nitrophenyl)amino)acrylonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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