1-isopropyl-2-phenyl-5,6,7,8-tetrahydroquinazoline-4(1H)-thione
TL;DR: 1-isopropyl-2-phenyl-5,6,7,8-tetrahydroquinazoline-4(1H)-thione (CAS 371218-86-9) is a chemical compound with molecular formula C17H20N2S and molecular weight 284.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-phenyl-1-propan-2-yl-5,6,7,8-tetrahydroquinazoline-4-thione
Also Known As: 1-isopropyl-2-phenyl-5,6,7,8-tetrahydroquinazoline-4(1H)-thione, 2-phenyl-1-(propan-2-yl)-1,4,5,6,7,8-hexahydroquinazoline-4-thione, 2-phenyl-1-propan-2-yl-5,6,7,8-tetrahydroquinazoline-4-thione, AF-399/40806160, F1013-0035
| Molecular Formula | C17H20N2S |
|---|---|
| Molecular Weight | 284.13 g/mol |
| LogP | 3.7 |
| Topological Polar Surface Area | 47.7 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 2 |
| Exact Mass | 284.1347 |
| Heavy Atoms | 20 |
| Complexity | 456.0 |
Chemical Identifiers
| CAS Number | 371218-86-9 |
|---|---|
| SMILES | CC(C)N1C2=C(CCCC2)C(=S)N=C1C3=CC=CC=C3 |
| InChIKey | DJPVGDDXCJKAOT-UHFFFAOYSA-N |
Product Overview
1-isopropyl-2-phenyl-5,6,7,8-tetrahydroquinazoline-4(1H)-thione (CAS 371218-86-9), with molecular formula C17H20N2S and molecular weight 284.13 g/mol. IUPAC: 2-phenyl-1-propan-2-yl-5,6,7,8-tetrahydroquinazoline-4-thione.
Chemical Property Profile of 1-isopropyl-2-phenyl-5,6,7,8-tetrahydroquinazoline-4(1H)-thione
Property Insights of 1-isopropyl-2-phenyl-5,6,7,8-tetrahydroquinazoline-4(1H)-thione
The XLogP value of 3.7 indicates that 1-isopropyl-2-phenyl-5,6,7,8-tetrahydroquinazoline-4(1H)-thione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 47.7 Ų, 1-isopropyl-2-phenyl-5,6,7,8-tetrahydroquinazoline-4(1H)-thione exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-isopropyl-2-phenyl-5,6,7,8-tetrahydroquinazoline-4(1H)-thione has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-isopropyl-2-phenyl-5,6,7,8-tetrahydroquinazoline-4(1H)-thione?
The CAS number of 1-isopropyl-2-phenyl-5,6,7,8-tetrahydroquinazoline-4(1H)-thione is 371218-86-9.
What is the molecular formula of 1-isopropyl-2-phenyl-5,6,7,8-tetrahydroquinazoline-4(1H)-thione?
The molecular formula of 1-isopropyl-2-phenyl-5,6,7,8-tetrahydroquinazoline-4(1H)-thione is C17H20N2S.
What is the molecular weight of 1-isopropyl-2-phenyl-5,6,7,8-tetrahydroquinazoline-4(1H)-thione?
The molecular weight of 1-isopropyl-2-phenyl-5,6,7,8-tetrahydroquinazoline-4(1H)-thione is 284.13 g/mol.
Where can I buy 1-isopropyl-2-phenyl-5,6,7,8-tetrahydroquinazoline-4(1H)-thione?
You can request a quote for 1-isopropyl-2-phenyl-5,6,7,8-tetrahydroquinazoline-4(1H)-thione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-isopropyl-2-phenyl-5,6,7,8-tetrahydroquinazoline-4(1H)-thione?
Yes, KEHONG BIO provides custom synthesis services for 1-isopropyl-2-phenyl-5,6,7,8-tetrahydroquinazoline-4(1H)-thione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.