(E)-2-(4-benzhydrylpiperazin-1-yl)-5-(thiophen-2-ylmethylene)thiazol-4(5H)-one
TL;DR: (E)-2-(4-benzhydrylpiperazin-1-yl)-5-(thiophen-2-ylmethylene)thiazol-4(5H)-one (CAS 371218-15-4) is a chemical compound with molecular formula C25H23N3OS2 and molecular weight 445.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5E)-2-(4-benzhydrylpiperazin-1-yl)-5-(thiophen-2-ylmethylidene)-1,3-thiazol-4-one
Also Known As: (5E)-2-(4-benzhydrylpiperazin-1-yl)-5-(thiophen-2-ylmethylidene)-1,3-thiazol-4-one, (E)-2-(4-benzhydrylpiperazin-1-yl)-5-(thiophen-2-ylmethylene)thiazol-4(5H)-one, 2-(4-benzhydrylpiperazin-1-yl)-5-(thiophen-2-ylmethylidene)-1,3-thiazol-4-one
| Molecular Formula | C25H23N3OS2 |
|---|---|
| Molecular Weight | 445.13 g/mol |
| LogP | 5.1256 |
| Topological Polar Surface Area | 35.91 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 445.12827 |
| Heavy Atoms | 31 |
| Complexity | 1046.8203 |
Chemical Identifiers
| CAS Number | 371218-15-4 |
|---|---|
| SMILES | C1CN(CCN1C2=NC(=O)/C(=C\C3=CC=CS3)/S2)C(C4=CC=CC=C4)C5=CC=CC=C5 |
Product Overview
(E)-2-(4-benzhydrylpiperazin-1-yl)-5-(thiophen-2-ylmethylene)thiazol-4(5H)-one (CAS 371218-15-4), with molecular formula C25H23N3OS2 and molecular weight 445.13 g/mol. IUPAC: (5E)-2-(4-benzhydrylpiperazin-1-yl)-5-(thiophen-2-ylmethylidene)-1,3-thiazol-4-one.
Chemical Property Profile of (E)-2-(4-benzhydrylpiperazin-1-yl)-5-(thiophen-2-ylmethylene)thiazol-4(5H)-one
Property Insights of (E)-2-(4-benzhydrylpiperazin-1-yl)-5-(thiophen-2-ylmethylene)thiazol-4(5H)-one
The XLogP value of 5.1256 indicates that (E)-2-(4-benzhydrylpiperazin-1-yl)-5-(thiophen-2-ylmethylene)thiazol-4(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.91 Ų, (E)-2-(4-benzhydrylpiperazin-1-yl)-5-(thiophen-2-ylmethylene)thiazol-4(5H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-2-(4-benzhydrylpiperazin-1-yl)-5-(thiophen-2-ylmethylene)thiazol-4(5H)-one has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-2-(4-benzhydrylpiperazin-1-yl)-5-(thiophen-2-ylmethylene)thiazol-4(5H)-one?
The CAS number of (E)-2-(4-benzhydrylpiperazin-1-yl)-5-(thiophen-2-ylmethylene)thiazol-4(5H)-one is 371218-15-4.
What is the molecular formula of (E)-2-(4-benzhydrylpiperazin-1-yl)-5-(thiophen-2-ylmethylene)thiazol-4(5H)-one?
The molecular formula of (E)-2-(4-benzhydrylpiperazin-1-yl)-5-(thiophen-2-ylmethylene)thiazol-4(5H)-one is C25H23N3OS2.
What is the molecular weight of (E)-2-(4-benzhydrylpiperazin-1-yl)-5-(thiophen-2-ylmethylene)thiazol-4(5H)-one?
The molecular weight of (E)-2-(4-benzhydrylpiperazin-1-yl)-5-(thiophen-2-ylmethylene)thiazol-4(5H)-one is 445.13 g/mol.
Where can I buy (E)-2-(4-benzhydrylpiperazin-1-yl)-5-(thiophen-2-ylmethylene)thiazol-4(5H)-one?
You can request a quote for (E)-2-(4-benzhydrylpiperazin-1-yl)-5-(thiophen-2-ylmethylene)thiazol-4(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-2-(4-benzhydrylpiperazin-1-yl)-5-(thiophen-2-ylmethylene)thiazol-4(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for (E)-2-(4-benzhydrylpiperazin-1-yl)-5-(thiophen-2-ylmethylene)thiazol-4(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.