![2-[2-Furan-2-yl-4-hydroxy-3-(4-methoxy-benzoyl)-5-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-thiazole-5-carb oxylic acid methyl ester structure](/static/products/371/371209-99-3.png)
2-[2-Furan-2-yl-4-hydroxy-3-(4-methoxy-benzoyl)-5-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-thiazole-5-carb oxylic acid methyl ester
TL;DR: 2-[2-Furan-2-yl-4-hydroxy-3-(4-methoxy-benzoyl)-5-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-thiazole-5-carb oxylic acid methyl ester (CAS 371209-99-3) is a chemical compound with molecular formula C22H18N2O7S and molecular weight 454.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
methyl 2-[(3E)-2-(furan-2-yl)-3-[hydroxy-(4-methoxyphenyl)methylidene]-4,5-dioxopyrrolidin-1-yl]-4-methyl-1,3-thiazole-5-carboxylate
Also Known As: 2-[2-Furan-2-yl-4-hydroxy-3-(4-methoxy-benzoyl)-5-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-thiazole-5-carb oxylic acid methyl ester, methyl 2-(2-(furan-2-yl)-4-hydroxy-3-(4-methoxybenzoyl)-5-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate, methyl 2-[(3E)-2-(furan-2-yl)-3-[hydroxy-(4-methoxyphenyl)methylidene]-4,5-dioxopyrrolidin-1-yl]-4-methyl-1,3-thiazole-5-carboxylate, methyl 2-{(3E)-2-(furan-2-yl)-3-[hydroxy(4-methoxyphenyl)methylidene]-4,5-dioxopyrrolidin-1-yl}-4-methyl-1,3-thiazole-5-carboxylate, methyl 2-{5-(2-furyl)-3-hydroxy-4-[(4-methoxyphenyl)carbonyl]-2-oxo(3-pyrrolin yl)}-4-methyl-1,3-thiazole-5-carboxylate
| Molecular Formula | C22H18N2O7S |
|---|---|
| Molecular Weight | 454.08 g/mol |
| LogP | 3.46602 |
| Topological Polar Surface Area | 119.17 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 5 |
| Exact Mass | 454.08347 |
| Heavy Atoms | 32 |
| Complexity | 1225.7177 |
Chemical Identifiers
| CAS Number | 371209-99-3 |
|---|---|
| SMILES | CC1=C(SC(=N1)N2C(/C(=C(/C3=CC=C(C=C3)OC)\O)/C(=O)C2=O)C4=CC=CO4)C(=O)OC |
Product Overview
2-[2-Furan-2-yl-4-hydroxy-3-(4-methoxy-benzoyl)-5-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-thiazole-5-carb oxylic acid methyl ester (CAS 371209-99-3), with molecular formula C22H18N2O7S and molecular weight 454.08 g/mol. IUPAC: methyl 2-[(3E)-2-(furan-2-yl)-3-[hydroxy-(4-methoxyphenyl)methylidene]-4,5-dioxopyrrolidin-1-yl]-4-methyl-1,3-thiazole-5-carboxylate.
Chemical Property Profile of 2-[2-Furan-2-yl-4-hydroxy-3-(4-methoxy-benzoyl)-5-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-thiazole-5-carb oxylic acid methyl ester
Property Insights of 2-[2-Furan-2-yl-4-hydroxy-3-(4-methoxy-benzoyl)-5-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-thiazole-5-carb oxylic acid methyl ester
The XLogP value of 3.46602 indicates that 2-[2-Furan-2-yl-4-hydroxy-3-(4-methoxy-benzoyl)-5-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-thiazole-5-carb oxylic acid methyl ester is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 119.17 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-[2-Furan-2-yl-4-hydroxy-3-(4-methoxy-benzoyl)-5-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-thiazole-5-carb oxylic acid methyl ester. Following Lipinski's Rule of Five, 2-[2-Furan-2-yl-4-hydroxy-3-(4-methoxy-benzoyl)-5-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-thiazole-5-carb oxylic acid methyl ester has 1 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-[2-Furan-2-yl-4-hydroxy-3-(4-methoxy-benzoyl)-5-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-thiazole-5-carb oxylic acid methyl ester?
The CAS number of 2-[2-Furan-2-yl-4-hydroxy-3-(4-methoxy-benzoyl)-5-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-thiazole-5-carb oxylic acid methyl ester is 371209-99-3.
What is the molecular formula of 2-[2-Furan-2-yl-4-hydroxy-3-(4-methoxy-benzoyl)-5-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-thiazole-5-carb oxylic acid methyl ester?
The molecular formula of 2-[2-Furan-2-yl-4-hydroxy-3-(4-methoxy-benzoyl)-5-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-thiazole-5-carb oxylic acid methyl ester is C22H18N2O7S.
What is the molecular weight of 2-[2-Furan-2-yl-4-hydroxy-3-(4-methoxy-benzoyl)-5-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-thiazole-5-carb oxylic acid methyl ester?
The molecular weight of 2-[2-Furan-2-yl-4-hydroxy-3-(4-methoxy-benzoyl)-5-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-thiazole-5-carb oxylic acid methyl ester is 454.08 g/mol.
Where can I buy 2-[2-Furan-2-yl-4-hydroxy-3-(4-methoxy-benzoyl)-5-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-thiazole-5-carb oxylic acid methyl ester?
You can request a quote for 2-[2-Furan-2-yl-4-hydroxy-3-(4-methoxy-benzoyl)-5-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-thiazole-5-carb oxylic acid methyl ester directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-[2-Furan-2-yl-4-hydroxy-3-(4-methoxy-benzoyl)-5-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-thiazole-5-carb oxylic acid methyl ester?
Yes, KEHONG BIO provides custom synthesis services for 2-[2-Furan-2-yl-4-hydroxy-3-(4-methoxy-benzoyl)-5-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-thiazole-5-carb oxylic acid methyl ester and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.