2-(3-Benzoyl-2-furan-2-yl-4-hydroxy-5-oxo-2,5-dihydro-pyrrol-1-yl)-4-methyl-thiazole-5-carboxylic acid methyl ester
TL;DR: 2-(3-Benzoyl-2-furan-2-yl-4-hydroxy-5-oxo-2,5-dihydro-pyrrol-1-yl)-4-methyl-thiazole-5-carboxylic acid methyl ester (CAS 371205-68-4) is a chemical compound with molecular formula C21H16N2O6S and molecular weight 424.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
methyl 2-[(3E)-2-(furan-2-yl)-3-[hydroxy(phenyl)methylidene]-4,5-dioxopyrrolidin-1-yl]-4-methyl-1,3-thiazole-5-carboxylate
Also Known As: 2-(3-Benzoyl-2-furan-2-yl-4-hydroxy-5-oxo-2,5-dihydro-pyrrol-1-yl)-4-methyl-thiazole-5-carboxylic acid methyl ester, methyl 2-(3-benzoyl-2-(furan-2-yl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate, methyl 2-[(3E)-2-(furan-2-yl)-3-[hydroxy(phenyl)methylidene]-4,5-dioxopyrrolidin-1-yl]-4-methyl-1,3-thiazole-5-carboxylate, methyl 2-[2-(furan-2-yl)-4-hydroxy-5-oxo-3-(phenylcarbonyl)-2,5-dihydro-1H-pyrrol-1-yl]-4-methyl-1,3-thiazole-5-carboxylate, methyl 2-[5-(2-furyl)-3-hydroxy-2-oxo-4-(phenylcarbonyl)(3-pyrrolinyl)]-4-meth yl-1,3-thiazole-5-carboxylate
| Molecular Formula | C21H16N2O6S |
|---|---|
| Molecular Weight | 424.07 g/mol |
| LogP | 3.45742 |
| Topological Polar Surface Area | 109.94 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 4 |
| Exact Mass | 424.0729 |
| Heavy Atoms | 30 |
| Complexity | 1163.5903 |
Chemical Identifiers
| CAS Number | 371205-68-4 |
|---|---|
| SMILES | CC1=C(SC(=N1)N2C(/C(=C(/C3=CC=CC=C3)\O)/C(=O)C2=O)C4=CC=CO4)C(=O)OC |
Product Overview
2-(3-Benzoyl-2-furan-2-yl-4-hydroxy-5-oxo-2,5-dihydro-pyrrol-1-yl)-4-methyl-thiazole-5-carboxylic acid methyl ester (CAS 371205-68-4), with molecular formula C21H16N2O6S and molecular weight 424.07 g/mol. IUPAC: methyl 2-[(3E)-2-(furan-2-yl)-3-[hydroxy(phenyl)methylidene]-4,5-dioxopyrrolidin-1-yl]-4-methyl-1,3-thiazole-5-carboxylate.
Chemical Property Profile of 2-(3-Benzoyl-2-furan-2-yl-4-hydroxy-5-oxo-2,5-dihydro-pyrrol-1-yl)-4-methyl-thiazole-5-carboxylic acid methyl ester
Property Insights of 2-(3-Benzoyl-2-furan-2-yl-4-hydroxy-5-oxo-2,5-dihydro-pyrrol-1-yl)-4-methyl-thiazole-5-carboxylic acid methyl ester
The XLogP value of 3.45742 indicates that 2-(3-Benzoyl-2-furan-2-yl-4-hydroxy-5-oxo-2,5-dihydro-pyrrol-1-yl)-4-methyl-thiazole-5-carboxylic acid methyl ester is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 109.94 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-(3-Benzoyl-2-furan-2-yl-4-hydroxy-5-oxo-2,5-dihydro-pyrrol-1-yl)-4-methyl-thiazole-5-carboxylic acid methyl ester. Following Lipinski's Rule of Five, 2-(3-Benzoyl-2-furan-2-yl-4-hydroxy-5-oxo-2,5-dihydro-pyrrol-1-yl)-4-methyl-thiazole-5-carboxylic acid methyl ester has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(3-Benzoyl-2-furan-2-yl-4-hydroxy-5-oxo-2,5-dihydro-pyrrol-1-yl)-4-methyl-thiazole-5-carboxylic acid methyl ester?
The CAS number of 2-(3-Benzoyl-2-furan-2-yl-4-hydroxy-5-oxo-2,5-dihydro-pyrrol-1-yl)-4-methyl-thiazole-5-carboxylic acid methyl ester is 371205-68-4.
What is the molecular formula of 2-(3-Benzoyl-2-furan-2-yl-4-hydroxy-5-oxo-2,5-dihydro-pyrrol-1-yl)-4-methyl-thiazole-5-carboxylic acid methyl ester?
The molecular formula of 2-(3-Benzoyl-2-furan-2-yl-4-hydroxy-5-oxo-2,5-dihydro-pyrrol-1-yl)-4-methyl-thiazole-5-carboxylic acid methyl ester is C21H16N2O6S.
What is the molecular weight of 2-(3-Benzoyl-2-furan-2-yl-4-hydroxy-5-oxo-2,5-dihydro-pyrrol-1-yl)-4-methyl-thiazole-5-carboxylic acid methyl ester?
The molecular weight of 2-(3-Benzoyl-2-furan-2-yl-4-hydroxy-5-oxo-2,5-dihydro-pyrrol-1-yl)-4-methyl-thiazole-5-carboxylic acid methyl ester is 424.07 g/mol.
Where can I buy 2-(3-Benzoyl-2-furan-2-yl-4-hydroxy-5-oxo-2,5-dihydro-pyrrol-1-yl)-4-methyl-thiazole-5-carboxylic acid methyl ester?
You can request a quote for 2-(3-Benzoyl-2-furan-2-yl-4-hydroxy-5-oxo-2,5-dihydro-pyrrol-1-yl)-4-methyl-thiazole-5-carboxylic acid methyl ester directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(3-Benzoyl-2-furan-2-yl-4-hydroxy-5-oxo-2,5-dihydro-pyrrol-1-yl)-4-methyl-thiazole-5-carboxylic acid methyl ester?
Yes, KEHONG BIO provides custom synthesis services for 2-(3-Benzoyl-2-furan-2-yl-4-hydroxy-5-oxo-2,5-dihydro-pyrrol-1-yl)-4-methyl-thiazole-5-carboxylic acid methyl ester and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.