4-(4-Amino-2,6-difluoro-phenyl)-tetrahydro-thiopyran-4-ol
TL;DR: 4-(4-Amino-2,6-difluoro-phenyl)-tetrahydro-thiopyran-4-ol (CAS 371195-40-3) is a chemical compound with molecular formula C11H13F2NOS and molecular weight 245.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(4-amino-2,6-difluorophenyl)thian-4-ol
Also Known As: 4-(4-amino-2,6-difluoro-phenyl)thian-4-ol, 2H-Thiopyran-4-ol, 4-(4-amino-2,6-difluorophenyl)tetrahydro-, 4-(4-Amino-2,6-difluoro-phenyl)-tetrahydro-thiopyran-4-ol, 4-(4-Amino-2,6-difluorophenyl)-tetrahydrothiopyran-4-ol, 4-(4-Amino-2,6-difluoro-phenyl)-tetrahydro-thiopyran-4-o1
| Molecular Formula | C11H13F2NOS |
|---|---|
| Molecular Weight | 245.07 g/mol |
| LogP | 2.2616 |
| Topological Polar Surface Area | 46.25 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 245.06859 |
| Heavy Atoms | 16 |
| Complexity | 381.9662 |
Chemical Identifiers
| CAS Number | 371195-40-3 |
|---|---|
| SMILES | C1CSCCC1(C2=C(C=C(C=C2F)N)F)O |
Product Overview
4-(4-Amino-2,6-difluoro-phenyl)-tetrahydro-thiopyran-4-ol (CAS 371195-40-3), with molecular formula C11H13F2NOS and molecular weight 245.07 g/mol. IUPAC: 4-(4-amino-2,6-difluorophenyl)thian-4-ol.
Chemical Property Profile of 4-(4-Amino-2,6-difluoro-phenyl)-tetrahydro-thiopyran-4-ol
Property Insights of 4-(4-Amino-2,6-difluoro-phenyl)-tetrahydro-thiopyran-4-ol
The XLogP value of 2.2616 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-(4-Amino-2,6-difluoro-phenyl)-tetrahydro-thiopyran-4-ol. With a topological polar surface area (TPSA) of 46.25 Ų, 4-(4-Amino-2,6-difluoro-phenyl)-tetrahydro-thiopyran-4-ol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-(4-Amino-2,6-difluoro-phenyl)-tetrahydro-thiopyran-4-ol has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(4-Amino-2,6-difluoro-phenyl)-tetrahydro-thiopyran-4-ol?
The CAS number of 4-(4-Amino-2,6-difluoro-phenyl)-tetrahydro-thiopyran-4-ol is 371195-40-3.
What is the molecular formula of 4-(4-Amino-2,6-difluoro-phenyl)-tetrahydro-thiopyran-4-ol?
The molecular formula of 4-(4-Amino-2,6-difluoro-phenyl)-tetrahydro-thiopyran-4-ol is C11H13F2NOS.
What is the molecular weight of 4-(4-Amino-2,6-difluoro-phenyl)-tetrahydro-thiopyran-4-ol?
The molecular weight of 4-(4-Amino-2,6-difluoro-phenyl)-tetrahydro-thiopyran-4-ol is 245.07 g/mol.
Where can I buy 4-(4-Amino-2,6-difluoro-phenyl)-tetrahydro-thiopyran-4-ol?
You can request a quote for 4-(4-Amino-2,6-difluoro-phenyl)-tetrahydro-thiopyran-4-ol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(4-Amino-2,6-difluoro-phenyl)-tetrahydro-thiopyran-4-ol?
Yes, KEHONG BIO provides custom synthesis services for 4-(4-Amino-2,6-difluoro-phenyl)-tetrahydro-thiopyran-4-ol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.