AM-807/14146350 structure

AM-807/14146350

TL;DR: AM-807/14146350 (CAS 371141-75-2) is a chemical compound with molecular formula C21H16F2N4O and molecular weight 378.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

6-amino-4-(3,4-difluorophenyl)-3-methyl-1-(4-methylphenyl)-4H-pyrano[3,2-d]pyrazole-5-carbonitrile

Also Known As: AM-807/14146350, 6-amino-4-(3,4-difluorophenyl)-3-methyl-1-(4-methylphenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile, 6-amino-4-(3,4-difluorophenyl)-3-methyl-1-(4-methylphenyl)-4H-pyrano[2,3-c]pyrazole-5-carbonitrile, 6-amino-4-(3,4-difluorophenyl)-3-methyl-1-(p-tolyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile

CAS: 371141-75-2
Molecular Formula C21H16F2N4O
Molecular Weight 378.13 g/mol
LogP 3.98552
Topological Polar Surface Area 76.86 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 4
Rotatable Bonds 2
Exact Mass 378.1292
Heavy Atoms 28
Complexity 1156.384

Chemical Identifiers

CAS Number 371141-75-2
SMILES CC1=CC=C(C=C1)N2C3=C(C(C(=C(O3)N)C#N)C4=CC(=C(C=C4)F)F)C(=N2)C

Product Overview

AM-807/14146350 (CAS 371141-75-2), with molecular formula C21H16F2N4O and molecular weight 378.13 g/mol. IUPAC: 6-amino-4-(3,4-difluorophenyl)-3-methyl-1-(4-methylphenyl)-4H-pyrano[3,2-d]pyrazole-5-carbonitrile.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of AM-807/14146350

XLogP
3.98552
TPSA (Topological Polar Surface Area)
76.86
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
4
Rotatable Bonds
2
Heavy Atoms
28
Complexity
1156.384
Exact Mass
378.1292
Monoisotopic Mass
378.1292
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of AM-807/14146350

The XLogP value of 3.98552 indicates that AM-807/14146350 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 76.86 Ų falls within the moderate polarity range, balancing permeability and solubility for AM-807/14146350. Following Lipinski's Rule of Five, AM-807/14146350 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of AM-807/14146350?

The CAS number of AM-807/14146350 is 371141-75-2.

What is the molecular formula of AM-807/14146350?

The molecular formula of AM-807/14146350 is C21H16F2N4O.

What is the molecular weight of AM-807/14146350?

The molecular weight of AM-807/14146350 is 378.13 g/mol.

Where can I buy AM-807/14146350?

You can request a quote for AM-807/14146350 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for AM-807/14146350?

Yes, KEHONG BIO provides custom synthesis services for AM-807/14146350 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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