methyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(3-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate
概要：methyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(3-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate（CAS 371140-19-1）是一种化学化合物，分子式为C22H17N3O8S，分子量为483.07 g/mol。河南科弘生物科技有限公司提供CRO/CDMO定制合成服务，支持克级到吨级规格。
methyl 2-[4-hydroxy-3-(5-methylfuran-2-carbonyl)-2-(3-nitrophenyl)-5-oxo-2H-pyrrol-1-yl]-4-methyl-1,3-thiazole-5-carboxylate
又称：methyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(3-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate, methyl 2-[(3E)-3-[hydroxy(5-methylfuran-2-yl)methylidene]-2-(3-nitrophenyl)-4,5-dioxopyrrolidin-1-yl]-4-methyl-1,3-thiazole-5-carboxylate, methyl 2-[4-hydroxy-3-(5-methylfuran-2-carbonyl)-2-(3-nitrophenyl)-5-oxo-2H-pyrrol-1-yl]-4-methyl-1,3-thiazole-5-carboxylate, methyl 2-{3-hydroxy-4-[(5-methyl(2-furyl))carbonyl]-5-(3-nitrophenyl)-2-oxo(3- pyrrolinyl)}-4-methyl-1,3-thiazole-5-carboxylate, methyl 2-{3-hydroxy-4-[(5-methylfuran-2-yl)carbonyl]-5-(3-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl}-4-methyl-1,3-thiazole-5-carboxylate
| 分子式 | C22H17N3O8S |
|---|---|
| 分子量 | 483.07 g/mol |
| LogP | 3.83064 |
| 拓扑极性表面积 | 153.08 Ų |
| 氢键供体数 | 1 |
| 氢键受体数 | 10 |
| 可旋转键数 | 6 |
| 精确质量 | 483.07364 |
| 重原子数 | 34 |
| 复杂度 | 1386.1917 |
化学标识符
| CAS 编号 | 371140-19-1 |
|---|---|
| SMILES | CC1=CC=C(O1)C(=O)C2=C(C(=O)N(C2C3=CC(=CC=C3)[N+](=O)[O-])C4=NC(=C(S4)C(=O)OC)C)O |
产品概述
methyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(3-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate（CAS 371140-19-1），分子式为C22H17N3O8S，分子量为483.07 g/mol。IUPAC名：methyl 2-[4-hydroxy-3-(5-methylfuran-2-carbonyl)-2-(3-nitrophenyl)-5-oxo-2H-pyrrol-1-yl]-4-methyl-1,3-thiazole-5-carboxylate。
methyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(3-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate化学性质概览
属性洞察：methyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(3-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate
methyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(3-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate的XLogP值为3.83064，表明该化合物具有亲脂性（脂溶性好），可能影响其吸收、分布和配方策略。 TPSA为153.08 Ų，极性较高，提示该化合物膜透过性可能受限但水溶性较好。 根据Lipinski五规则，methyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(3-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate有1个氢键供体和10个氢键受体，均在类药范围内，提示具有较好的口服生物利用度潜力。
常见问题
常见问题
methyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(3-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate的CAS号是多少？
methyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(3-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate的CAS号为371140-19-1。
methyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(3-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate的分子式是什么？
methyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(3-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate的分子式为C22H17N3O8S。
methyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(3-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate的分子量是多少？
methyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(3-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate的分子量为483.07 g/mol。
在哪里可以购买methyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(3-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate？
您可以直接向科弘生物询价methyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(3-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate。联系我们或发送邮件至info@kehongbio.com获取报价和库存信息。
科弘生物是否提供methyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(3-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate的定制合成服务？
是的，科弘生物提供methyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(3-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate及相关化合物的定制合成服务。请联系我们并告知您的具体需求，包括数量、纯度和交期。