![(5E)-5-[(4-tert-butylphenyl)methylidene]-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4-one structure](/static/products/3711/371136-40-2.webp)
(5E)-5-[(4-tert-butylphenyl)methylidene]-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4-one
TL;DR: (5E)-5-[(4-tert-butylphenyl)methylidene]-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4-one (CAS 371136-40-2) is a chemical compound with molecular formula C24H26N4O3S and molecular weight 450.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5E)-5-[(4-tert-butylphenyl)methylidene]-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4-one
Also Known As: (5E)-5-[(4-tert-butylphenyl)methylidene]-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4-one, (E)-5-(4-(tert-butyl)benzylidene)-2-(4-(2-nitrophenyl)piperazin-1-yl)thiazol-4(5H)-one, 2-[4-(2-nitrophenyl)piperazin-1-yl]-5-[(4-tert-butylphenyl)methylidene]-1,3-thiazol-4-one, (5E)-5-(4-tert-butylbenzylidene)-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one
| Molecular Formula | C24H26N4O3S |
|---|---|
| Molecular Weight | 450.17 g/mol |
| LogP | 4.6848 |
| Topological Polar Surface Area | 79.05 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 450.17258 |
| Heavy Atoms | 32 |
| Complexity | 1094.9725 |
Chemical Identifiers
| CAS Number | 371136-40-2 |
|---|---|
| SMILES | CC(C)(C)C1=CC=C(C=C1)/C=C/2\C(=O)N=C(S2)N3CCN(CC3)C4=CC=CC=C4[N+](=O)[O-] |
Product Overview
(5E)-5-[(4-tert-butylphenyl)methylidene]-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4-one (CAS 371136-40-2), with molecular formula C24H26N4O3S and molecular weight 450.17 g/mol. IUPAC: (5E)-5-[(4-tert-butylphenyl)methylidene]-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4-one.
Chemical Property Profile of (5E)-5-[(4-tert-butylphenyl)methylidene]-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4-one
Property Insights of (5E)-5-[(4-tert-butylphenyl)methylidene]-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4-one
The XLogP value of 4.6848 indicates that (5E)-5-[(4-tert-butylphenyl)methylidene]-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 79.05 Ų falls within the moderate polarity range, balancing permeability and solubility for (5E)-5-[(4-tert-butylphenyl)methylidene]-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4-one. Following Lipinski's Rule of Five, (5E)-5-[(4-tert-butylphenyl)methylidene]-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4-one has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (5E)-5-[(4-tert-butylphenyl)methylidene]-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4-one?
The CAS number of (5E)-5-[(4-tert-butylphenyl)methylidene]-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4-one is 371136-40-2.
What is the molecular formula of (5E)-5-[(4-tert-butylphenyl)methylidene]-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4-one?
The molecular formula of (5E)-5-[(4-tert-butylphenyl)methylidene]-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4-one is C24H26N4O3S.
What is the molecular weight of (5E)-5-[(4-tert-butylphenyl)methylidene]-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4-one?
The molecular weight of (5E)-5-[(4-tert-butylphenyl)methylidene]-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4-one is 450.17 g/mol.
Where can I buy (5E)-5-[(4-tert-butylphenyl)methylidene]-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4-one?
You can request a quote for (5E)-5-[(4-tert-butylphenyl)methylidene]-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (5E)-5-[(4-tert-butylphenyl)methylidene]-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4-one?
Yes, KEHONG BIO provides custom synthesis services for (5E)-5-[(4-tert-butylphenyl)methylidene]-2-[4-(2-nitrophenyl)piperazin-1-yl]-1,3-thiazol-4-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.