AF-399/42100520
TL;DR: AF-399/42100520 (CAS 371132-26-2) is a chemical compound with molecular formula C24H22N2O5 and molecular weight 418.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4E)-5-(furan-2-yl)-4-[hydroxy-(4-propan-2-yloxyphenyl)methylidene]-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione
Also Known As: AF-399/42100520, 5-(furan-2-yl)-3-hydroxy-4-(4-isopropoxybenzoyl)-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one, (4E)-5-(furan-2-yl)-4-[hydroxy-(4-propan-2-yloxyphenyl)methylidene]-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione, (4E)-5-(furan-2-yl)-4-{hydroxy[4-(propan-2-yloxy)phenyl]methylidene}-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione, 5-(2-furyl)-3-hydroxy-4-(4-isopropoxybenzoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
| Molecular Formula | C24H22N2O5 |
|---|---|
| Molecular Weight | 418.15 g/mol |
| LogP | 4.0837 |
| Topological Polar Surface Area | 92.87 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 418.15286 |
| Heavy Atoms | 31 |
| Complexity | 1102.641 |
Chemical Identifiers
| CAS Number | 371132-26-2 |
|---|---|
| SMILES | CC(C)OC1=CC=C(C=C1)/C(=C\2/C(N(C(=O)C2=O)CC3=CN=CC=C3)C4=CC=CO4)/O |
Product Overview
AF-399/42100520 (CAS 371132-26-2), with molecular formula C24H22N2O5 and molecular weight 418.15 g/mol. IUPAC: (4E)-5-(furan-2-yl)-4-[hydroxy-(4-propan-2-yloxyphenyl)methylidene]-1-(pyridin-3-ylmethyl)pyrrolidine-2,3-dione.
Chemical Property Profile of AF-399/42100520
Property Insights of AF-399/42100520
The XLogP value of 4.0837 indicates that AF-399/42100520 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 92.87 Ų falls within the moderate polarity range, balancing permeability and solubility for AF-399/42100520. Following Lipinski's Rule of Five, AF-399/42100520 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AF-399/42100520?
The CAS number of AF-399/42100520 is 371132-26-2.
What is the molecular formula of AF-399/42100520?
The molecular formula of AF-399/42100520 is C24H22N2O5.
What is the molecular weight of AF-399/42100520?
The molecular weight of AF-399/42100520 is 418.15 g/mol.
Where can I buy AF-399/42100520?
You can request a quote for AF-399/42100520 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AF-399/42100520?
Yes, KEHONG BIO provides custom synthesis services for AF-399/42100520 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.