ethyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(4-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate
概要：ethyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(4-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate（CAS 371128-28-8）是一种化学化合物，分子式为C23H19N3O8S，分子量为497.09 g/mol。河南科弘生物科技有限公司提供CRO/CDMO定制合成服务，支持克级到吨级规格。
ethyl 2-[4-hydroxy-3-(5-methylfuran-2-carbonyl)-2-(4-nitrophenyl)-5-oxo-2H-pyrrol-1-yl]-4-methyl-1,3-thiazole-5-carboxylate
又称：ethyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(4-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate, ethyl 2-[(3E)-3-[hydroxy(5-methylfuran-2-yl)methylidene]-2-(4-nitrophenyl)-4,5-dioxopyrrolidin-1-yl]-4-methyl-1,3-thiazole-5-carboxylate, ethyl 2-[3-hydroxy-4-(5-methyl-2-furoyl)-5-(4-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl]-4-methyl-1,3-thiazole-5-carboxylate, ethyl 2-[4-hydroxy-3-(5-methylfuran-2-carbonyl)-2-(4-nitrophenyl)-5-oxo-2H-pyrrol-1-yl]-4-methyl-1,3-thiazole-5-carboxylate, ethyl 2-{3-hydroxy-4-[(5-methyl(2-furyl))carbonyl]-5-(4-nitrophenyl)-2-oxo(3-p yrrolinyl)}-4-methyl-1,3-thiazole-5-carboxylate
| 分子式 | C23H19N3O8S |
|---|---|
| 分子量 | 497.09 g/mol |
| LogP | 4.22074 |
| 拓扑极性表面积 | 153.08 Ų |
| 氢键供体数 | 1 |
| 氢键受体数 | 10 |
| 可旋转键数 | 7 |
| 精确质量 | 497.0893 |
| 重原子数 | 35 |
| 复杂度 | 1385.886 |
化学标识符
| CAS 编号 | 371128-28-8 |
|---|---|
| SMILES | CCOC(=O)C1=C(N=C(S1)N2C(C(=C(C2=O)O)C(=O)C3=CC=C(O3)C)C4=CC=C(C=C4)[N+](=O)[O-])C |
产品概述
ethyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(4-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate（CAS 371128-28-8），分子式为C23H19N3O8S，分子量为497.09 g/mol。IUPAC名：ethyl 2-[4-hydroxy-3-(5-methylfuran-2-carbonyl)-2-(4-nitrophenyl)-5-oxo-2H-pyrrol-1-yl]-4-methyl-1,3-thiazole-5-carboxylate。
ethyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(4-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate化学性质概览
属性洞察：ethyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(4-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate
ethyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(4-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate的XLogP值为4.22074，表明该化合物具有亲脂性（脂溶性好），可能影响其吸收、分布和配方策略。 TPSA为153.08 Ų，极性较高，提示该化合物膜透过性可能受限但水溶性较好。 根据Lipinski五规则，ethyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(4-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate有1个氢键供体和10个氢键受体，均在类药范围内，提示具有较好的口服生物利用度潜力。
常见问题
常见问题
ethyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(4-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate的CAS号是多少？
ethyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(4-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate的CAS号为371128-28-8。
ethyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(4-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate的分子式是什么？
ethyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(4-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate的分子式为C23H19N3O8S。
ethyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(4-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate的分子量是多少？
ethyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(4-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate的分子量为497.09 g/mol。
在哪里可以购买ethyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(4-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate？
您可以直接向科弘生物询价ethyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(4-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate。联系我们或发送邮件至info@kehongbio.com获取报价和库存信息。
科弘生物是否提供ethyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(4-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate的定制合成服务？
是的，科弘生物提供ethyl 2-(3-hydroxy-4-(5-methylfuran-2-carbonyl)-5-(4-nitrophenyl)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate及相关化合物的定制合成服务。请联系我们并告知您的具体需求，包括数量、纯度和交期。