F1436-0444
TL;DR: F1436-0444 (CAS 371125-36-9) is a chemical compound with molecular formula C18H16ClN3OS2 and molecular weight 389.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5E)-2-[4-(4-chlorophenyl)piperazin-1-yl]-5-(thiophen-2-ylmethylidene)-1,3-thiazol-4-one
Also Known As: F1436-0444, (E)-2-(4-(4-chlorophenyl)piperazin-1-yl)-5-(thiophen-2-ylmethylene)thiazol-4(5H)-one, (5E)-2-[4-(4-chlorophenyl)piperazin-1-yl]-5-(thiophen-2-ylmethylidene)-1,3-thiazol-4-one, 2-[4-(4-chlorophenyl)-1-piperazinyl]-5-(2-thienylmethylene)-1,3-thiazol-4(5H)-one, (5E)-2-[4-(4-chlorophenyl)piperazin-1-yl]-5-(thiophen-2-ylmethylidene)-1,3-thiazol-4(5H)-one
| Molecular Formula | C18H16ClN3OS2 |
|---|---|
| Molecular Weight | 389.04 g/mol |
| LogP | 4.194 |
| Topological Polar Surface Area | 35.91 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 389.04233 |
| Heavy Atoms | 25 |
| Complexity | 822.51587 |
Chemical Identifiers
| CAS Number | 371125-36-9 |
|---|---|
| SMILES | C1CN(CCN1C2=CC=C(C=C2)Cl)C3=NC(=O)/C(=C\C4=CC=CS4)/S3 |
Product Overview
F1436-0444 (CAS 371125-36-9), with molecular formula C18H16ClN3OS2 and molecular weight 389.04 g/mol. IUPAC: (5E)-2-[4-(4-chlorophenyl)piperazin-1-yl]-5-(thiophen-2-ylmethylidene)-1,3-thiazol-4-one.
Chemical Property Profile of F1436-0444
Property Insights of F1436-0444
The XLogP value of 4.194 indicates that F1436-0444 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.91 Ų, F1436-0444 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, F1436-0444 has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F1436-0444?
The CAS number of F1436-0444 is 371125-36-9.
What is the molecular formula of F1436-0444?
The molecular formula of F1436-0444 is C18H16ClN3OS2.
What is the molecular weight of F1436-0444?
The molecular weight of F1436-0444 is 389.04 g/mol.
Where can I buy F1436-0444?
You can request a quote for F1436-0444 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F1436-0444?
Yes, KEHONG BIO provides custom synthesis services for F1436-0444 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.