5-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1-phenethyl-1H-pyrrol-2(5H)-one
TL;DR: 5-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1-phenethyl-1H-pyrrol-2(5H)-one (CAS 371123-75-0) is a chemical compound with molecular formula C26H22FNO3 and molecular weight 415.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4E)-5-(4-fluorophenyl)-4-[hydroxy-(4-methylphenyl)methylidene]-1-(2-phenylethyl)pyrrolidine-2,3-dione
Also Known As: 5-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1-phenethyl-1H-pyrrol-2(5H)-one, (4E)-5-(4-fluorophenyl)-4-[hydroxy(4-methylphenyl)methylidene]-1-(2-phenylethyl)pyrrolidine-2,3-dione, (4E)-5-(4-fluorophenyl)-4-[hydroxy-(4-methylphenyl)methylidene]-1-phenethylpyrrolidine-2,3-dione
| Molecular Formula | C26H22FNO3 |
|---|---|
| Molecular Weight | 415.16 g/mol |
| LogP | 4.79852 |
| Topological Polar Surface Area | 57.61 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 415.1584 |
| Heavy Atoms | 31 |
| Complexity | 1135.5343 |
Chemical Identifiers
| CAS Number | 371123-75-0 |
|---|---|
| SMILES | CC1=CC=C(C=C1)/C(=C\2/C(N(C(=O)C2=O)CCC3=CC=CC=C3)C4=CC=C(C=C4)F)/O |
Product Overview
5-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1-phenethyl-1H-pyrrol-2(5H)-one (CAS 371123-75-0), with molecular formula C26H22FNO3 and molecular weight 415.16 g/mol. IUPAC: (4E)-5-(4-fluorophenyl)-4-[hydroxy-(4-methylphenyl)methylidene]-1-(2-phenylethyl)pyrrolidine-2,3-dione.
Chemical Property Profile of 5-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1-phenethyl-1H-pyrrol-2(5H)-one
Property Insights of 5-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1-phenethyl-1H-pyrrol-2(5H)-one
The XLogP value of 4.79852 indicates that 5-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1-phenethyl-1H-pyrrol-2(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.61 Ų, 5-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1-phenethyl-1H-pyrrol-2(5H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1-phenethyl-1H-pyrrol-2(5H)-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1-phenethyl-1H-pyrrol-2(5H)-one?
The CAS number of 5-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1-phenethyl-1H-pyrrol-2(5H)-one is 371123-75-0.
What is the molecular formula of 5-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1-phenethyl-1H-pyrrol-2(5H)-one?
The molecular formula of 5-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1-phenethyl-1H-pyrrol-2(5H)-one is C26H22FNO3.
What is the molecular weight of 5-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1-phenethyl-1H-pyrrol-2(5H)-one?
The molecular weight of 5-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1-phenethyl-1H-pyrrol-2(5H)-one is 415.16 g/mol.
Where can I buy 5-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1-phenethyl-1H-pyrrol-2(5H)-one?
You can request a quote for 5-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1-phenethyl-1H-pyrrol-2(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1-phenethyl-1H-pyrrol-2(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for 5-(4-fluorophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1-phenethyl-1H-pyrrol-2(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.