![(5E)-5-[[4-[(4-nitrophenyl)methoxy]phenyl]methylidene]-2-piperidin-1-yl-1,3-thiazol-4-one structure](/static/products/3711/371117-83-8.webp)
(5E)-5-[[4-[(4-nitrophenyl)methoxy]phenyl]methylidene]-2-piperidin-1-yl-1,3-thiazol-4-one
TL;DR: (5E)-5-[[4-[(4-nitrophenyl)methoxy]phenyl]methylidene]-2-piperidin-1-yl-1,3-thiazol-4-one (CAS 371117-83-8) is a chemical compound with molecular formula C22H21N3O4S and molecular weight 423.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5E)-5-[[4-[(4-nitrophenyl)methoxy]phenyl]methylidene]-2-piperidin-1-yl-1,3-thiazol-4-one
Also Known As: (5E)-5-[[4-[(4-nitrophenyl)methoxy]phenyl]methylidene]-2-piperidin-1-yl-1,3-thiazol-4-one, (5E)-5-{4-[(4-nitrobenzyl)oxy]benzylidene}-2-(piperidin-1-yl)-1,3-thiazol-4(5H)-one, (E)-5-(4-((4-nitrobenzyl)oxy)benzylidene)-2-(piperidin-1-yl)thiazol-4(5H)-one, 5-[[4-[(4-nitrophenyl)methoxy]phenyl]methylidene]-2-(1-piperidyl)-1,3-thiazol-4-one
| Molecular Formula | C22H21N3O4S |
|---|---|
| Molecular Weight | 423.13 g/mol |
| LogP | 4.63 |
| Topological Polar Surface Area | 85.04 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 423.12527 |
| Heavy Atoms | 30 |
| Complexity | 994.04767 |
Chemical Identifiers
| CAS Number | 371117-83-8 |
|---|---|
| SMILES | C1CCN(CC1)C2=NC(=O)/C(=C\C3=CC=C(C=C3)OCC4=CC=C(C=C4)[N+](=O)[O-])/S2 |
Product Overview
(5E)-5-[[4-[(4-nitrophenyl)methoxy]phenyl]methylidene]-2-piperidin-1-yl-1,3-thiazol-4-one (CAS 371117-83-8), with molecular formula C22H21N3O4S and molecular weight 423.13 g/mol. IUPAC: (5E)-5-[[4-[(4-nitrophenyl)methoxy]phenyl]methylidene]-2-piperidin-1-yl-1,3-thiazol-4-one.
Chemical Property Profile of (5E)-5-[[4-[(4-nitrophenyl)methoxy]phenyl]methylidene]-2-piperidin-1-yl-1,3-thiazol-4-one
Property Insights of (5E)-5-[[4-[(4-nitrophenyl)methoxy]phenyl]methylidene]-2-piperidin-1-yl-1,3-thiazol-4-one
The XLogP value of 4.63 indicates that (5E)-5-[[4-[(4-nitrophenyl)methoxy]phenyl]methylidene]-2-piperidin-1-yl-1,3-thiazol-4-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 85.04 Ų falls within the moderate polarity range, balancing permeability and solubility for (5E)-5-[[4-[(4-nitrophenyl)methoxy]phenyl]methylidene]-2-piperidin-1-yl-1,3-thiazol-4-one. Following Lipinski's Rule of Five, (5E)-5-[[4-[(4-nitrophenyl)methoxy]phenyl]methylidene]-2-piperidin-1-yl-1,3-thiazol-4-one has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (5E)-5-[[4-[(4-nitrophenyl)methoxy]phenyl]methylidene]-2-piperidin-1-yl-1,3-thiazol-4-one?
The CAS number of (5E)-5-[[4-[(4-nitrophenyl)methoxy]phenyl]methylidene]-2-piperidin-1-yl-1,3-thiazol-4-one is 371117-83-8.
What is the molecular formula of (5E)-5-[[4-[(4-nitrophenyl)methoxy]phenyl]methylidene]-2-piperidin-1-yl-1,3-thiazol-4-one?
The molecular formula of (5E)-5-[[4-[(4-nitrophenyl)methoxy]phenyl]methylidene]-2-piperidin-1-yl-1,3-thiazol-4-one is C22H21N3O4S.
What is the molecular weight of (5E)-5-[[4-[(4-nitrophenyl)methoxy]phenyl]methylidene]-2-piperidin-1-yl-1,3-thiazol-4-one?
The molecular weight of (5E)-5-[[4-[(4-nitrophenyl)methoxy]phenyl]methylidene]-2-piperidin-1-yl-1,3-thiazol-4-one is 423.13 g/mol.
Where can I buy (5E)-5-[[4-[(4-nitrophenyl)methoxy]phenyl]methylidene]-2-piperidin-1-yl-1,3-thiazol-4-one?
You can request a quote for (5E)-5-[[4-[(4-nitrophenyl)methoxy]phenyl]methylidene]-2-piperidin-1-yl-1,3-thiazol-4-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (5E)-5-[[4-[(4-nitrophenyl)methoxy]phenyl]methylidene]-2-piperidin-1-yl-1,3-thiazol-4-one?
Yes, KEHONG BIO provides custom synthesis services for (5E)-5-[[4-[(4-nitrophenyl)methoxy]phenyl]methylidene]-2-piperidin-1-yl-1,3-thiazol-4-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.