5-(4-fluorophenyl)-3-hydroxy-4-(4-isopropoxybenzoyl)-1-(pyridin-2-yl)-1H-pyrrol-2(5H)-one
TL;DR: 5-(4-fluorophenyl)-3-hydroxy-4-(4-isopropoxybenzoyl)-1-(pyridin-2-yl)-1H-pyrrol-2(5H)-one (CAS 370869-74-2) is a chemical compound with molecular formula C25H21FN2O4 and molecular weight 432.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4E)-5-(4-fluorophenyl)-4-[hydroxy-(4-propan-2-yloxyphenyl)methylidene]-1-pyridin-2-ylpyrrolidine-2,3-dione
Also Known As: 5-(4-fluorophenyl)-3-hydroxy-4-(4-isopropoxybenzoyl)-1-(pyridin-2-yl)-1H-pyrrol-2(5H)-one, (4E)-5-(4-fluorophenyl)-4-[hydroxy-(4-propan-2-yloxyphenyl)methylidene]-1-pyridin-2-ylpyrrolidine-2,3-dione, (4E)-5-(4-fluorophenyl)-4-{hydroxy[4-(propan-2-yloxy)phenyl]methylidene}-1-(pyridin-2-yl)pyrrolidine-2,3-dione, 5-(4-fluorophenyl)-3-hydroxy-4-(4-isopropoxybenzoyl)-1-(2-pyridinyl)-1,5-dihydro-2H-pyrrol-2-one, 5-(4-fluorophenyl)-3-hydroxy-4-{[4-(methylethoxy)phenyl]carbonyl}-1-(2-pyridyl )-3-pyrrolin-2-one
| Molecular Formula | C25H21FN2O4 |
|---|---|
| Molecular Weight | 432.15 g/mol |
| LogP | 4.6342 |
| Topological Polar Surface Area | 79.73 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 432.14853 |
| Heavy Atoms | 32 |
| Complexity | 1172.8285 |
Chemical Identifiers
| CAS Number | 370869-74-2 |
|---|---|
| SMILES | CC(C)OC1=CC=C(C=C1)/C(=C\2/C(N(C(=O)C2=O)C3=CC=CC=N3)C4=CC=C(C=C4)F)/O |
Product Overview
5-(4-fluorophenyl)-3-hydroxy-4-(4-isopropoxybenzoyl)-1-(pyridin-2-yl)-1H-pyrrol-2(5H)-one (CAS 370869-74-2), with molecular formula C25H21FN2O4 and molecular weight 432.15 g/mol. IUPAC: (4E)-5-(4-fluorophenyl)-4-[hydroxy-(4-propan-2-yloxyphenyl)methylidene]-1-pyridin-2-ylpyrrolidine-2,3-dione.
Chemical Property Profile of 5-(4-fluorophenyl)-3-hydroxy-4-(4-isopropoxybenzoyl)-1-(pyridin-2-yl)-1H-pyrrol-2(5H)-one
Property Insights of 5-(4-fluorophenyl)-3-hydroxy-4-(4-isopropoxybenzoyl)-1-(pyridin-2-yl)-1H-pyrrol-2(5H)-one
The XLogP value of 4.6342 indicates that 5-(4-fluorophenyl)-3-hydroxy-4-(4-isopropoxybenzoyl)-1-(pyridin-2-yl)-1H-pyrrol-2(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 79.73 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-(4-fluorophenyl)-3-hydroxy-4-(4-isopropoxybenzoyl)-1-(pyridin-2-yl)-1H-pyrrol-2(5H)-one. Following Lipinski's Rule of Five, 5-(4-fluorophenyl)-3-hydroxy-4-(4-isopropoxybenzoyl)-1-(pyridin-2-yl)-1H-pyrrol-2(5H)-one has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-(4-fluorophenyl)-3-hydroxy-4-(4-isopropoxybenzoyl)-1-(pyridin-2-yl)-1H-pyrrol-2(5H)-one?
The CAS number of 5-(4-fluorophenyl)-3-hydroxy-4-(4-isopropoxybenzoyl)-1-(pyridin-2-yl)-1H-pyrrol-2(5H)-one is 370869-74-2.
What is the molecular formula of 5-(4-fluorophenyl)-3-hydroxy-4-(4-isopropoxybenzoyl)-1-(pyridin-2-yl)-1H-pyrrol-2(5H)-one?
The molecular formula of 5-(4-fluorophenyl)-3-hydroxy-4-(4-isopropoxybenzoyl)-1-(pyridin-2-yl)-1H-pyrrol-2(5H)-one is C25H21FN2O4.
What is the molecular weight of 5-(4-fluorophenyl)-3-hydroxy-4-(4-isopropoxybenzoyl)-1-(pyridin-2-yl)-1H-pyrrol-2(5H)-one?
The molecular weight of 5-(4-fluorophenyl)-3-hydroxy-4-(4-isopropoxybenzoyl)-1-(pyridin-2-yl)-1H-pyrrol-2(5H)-one is 432.15 g/mol.
Where can I buy 5-(4-fluorophenyl)-3-hydroxy-4-(4-isopropoxybenzoyl)-1-(pyridin-2-yl)-1H-pyrrol-2(5H)-one?
You can request a quote for 5-(4-fluorophenyl)-3-hydroxy-4-(4-isopropoxybenzoyl)-1-(pyridin-2-yl)-1H-pyrrol-2(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-(4-fluorophenyl)-3-hydroxy-4-(4-isopropoxybenzoyl)-1-(pyridin-2-yl)-1H-pyrrol-2(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for 5-(4-fluorophenyl)-3-hydroxy-4-(4-isopropoxybenzoyl)-1-(pyridin-2-yl)-1H-pyrrol-2(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.