![5-(3-bromophenyl)-3-hydroxy-4-{[4-(propan-2-yloxy)phenyl]carbonyl}-1-(1,3-thiazol-2-yl)-1,5-dihydro-2H-pyrrol-2-one structure](/static/products/370/370869-24-2.png)
5-(3-bromophenyl)-3-hydroxy-4-{[4-(propan-2-yloxy)phenyl]carbonyl}-1-(1,3-thiazol-2-yl)-1,5-dihydro-2H-pyrrol-2-one
TL;DR: 5-(3-bromophenyl)-3-hydroxy-4-{[4-(propan-2-yloxy)phenyl]carbonyl}-1-(1,3-thiazol-2-yl)-1,5-dihydro-2H-pyrrol-2-one (CAS 370869-24-2) is a chemical compound with molecular formula C23H19BrN2O4S and molecular weight 498.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4E)-5-(3-bromophenyl)-4-[hydroxy-(4-propan-2-yloxyphenyl)methylidene]-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione
Also Known As: 5-(3-bromophenyl)-3-hydroxy-4-{[4-(propan-2-yloxy)phenyl]carbonyl}-1-(1,3-thiazol-2-yl)-1,5-dihydro-2H-pyrrol-2-one, 5-(3-bromophenyl)-3-hydroxy-4-(4-isopropoxybenzoyl)-1-(thiazol-2-yl)-1H-pyrrol-2(5H)-one, (4E)-5-(3-bromophenyl)-4-[hydroxy-(4-propan-2-yloxyphenyl)methylidene]-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione, (4E)-5-(3-bromophenyl)-4-{hydroxy[4-(propan-2-yloxy)phenyl]methylidene}-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione, 5-(3-bromophenyl)-3-hydroxy-4-{[4-(methylethoxy)phenyl]carbonyl}-1-(1,3-thiazo l-2-yl)-3-pyrrolin-2-one
| Molecular Formula | C23H19BrN2O4S |
|---|---|
| Molecular Weight | 498.02 g/mol |
| LogP | 5.3191 |
| Topological Polar Surface Area | 79.73 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 498.0249 |
| Heavy Atoms | 31 |
| Complexity | 1156.5842 |
Chemical Identifiers
| CAS Number | 370869-24-2 |
|---|---|
| SMILES | CC(C)OC1=CC=C(C=C1)/C(=C\2/C(N(C(=O)C2=O)C3=NC=CS3)C4=CC(=CC=C4)Br)/O |
Product Overview
5-(3-bromophenyl)-3-hydroxy-4-{[4-(propan-2-yloxy)phenyl]carbonyl}-1-(1,3-thiazol-2-yl)-1,5-dihydro-2H-pyrrol-2-one (CAS 370869-24-2), with molecular formula C23H19BrN2O4S and molecular weight 498.02 g/mol. IUPAC: (4E)-5-(3-bromophenyl)-4-[hydroxy-(4-propan-2-yloxyphenyl)methylidene]-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione.
Chemical Property Profile of 5-(3-bromophenyl)-3-hydroxy-4-{[4-(propan-2-yloxy)phenyl]carbonyl}-1-(1,3-thiazol-2-yl)-1,5-dihydro-2H-pyrrol-2-one
Property Insights of 5-(3-bromophenyl)-3-hydroxy-4-{[4-(propan-2-yloxy)phenyl]carbonyl}-1-(1,3-thiazol-2-yl)-1,5-dihydro-2H-pyrrol-2-one
The XLogP value of 5.3191 indicates that 5-(3-bromophenyl)-3-hydroxy-4-{[4-(propan-2-yloxy)phenyl]carbonyl}-1-(1,3-thiazol-2-yl)-1,5-dihydro-2H-pyrrol-2-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 79.73 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-(3-bromophenyl)-3-hydroxy-4-{[4-(propan-2-yloxy)phenyl]carbonyl}-1-(1,3-thiazol-2-yl)-1,5-dihydro-2H-pyrrol-2-one. Following Lipinski's Rule of Five, 5-(3-bromophenyl)-3-hydroxy-4-{[4-(propan-2-yloxy)phenyl]carbonyl}-1-(1,3-thiazol-2-yl)-1,5-dihydro-2H-pyrrol-2-one has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-(3-bromophenyl)-3-hydroxy-4-{[4-(propan-2-yloxy)phenyl]carbonyl}-1-(1,3-thiazol-2-yl)-1,5-dihydro-2H-pyrrol-2-one?
The CAS number of 5-(3-bromophenyl)-3-hydroxy-4-{[4-(propan-2-yloxy)phenyl]carbonyl}-1-(1,3-thiazol-2-yl)-1,5-dihydro-2H-pyrrol-2-one is 370869-24-2.
What is the molecular formula of 5-(3-bromophenyl)-3-hydroxy-4-{[4-(propan-2-yloxy)phenyl]carbonyl}-1-(1,3-thiazol-2-yl)-1,5-dihydro-2H-pyrrol-2-one?
The molecular formula of 5-(3-bromophenyl)-3-hydroxy-4-{[4-(propan-2-yloxy)phenyl]carbonyl}-1-(1,3-thiazol-2-yl)-1,5-dihydro-2H-pyrrol-2-one is C23H19BrN2O4S.
What is the molecular weight of 5-(3-bromophenyl)-3-hydroxy-4-{[4-(propan-2-yloxy)phenyl]carbonyl}-1-(1,3-thiazol-2-yl)-1,5-dihydro-2H-pyrrol-2-one?
The molecular weight of 5-(3-bromophenyl)-3-hydroxy-4-{[4-(propan-2-yloxy)phenyl]carbonyl}-1-(1,3-thiazol-2-yl)-1,5-dihydro-2H-pyrrol-2-one is 498.02 g/mol.
Where can I buy 5-(3-bromophenyl)-3-hydroxy-4-{[4-(propan-2-yloxy)phenyl]carbonyl}-1-(1,3-thiazol-2-yl)-1,5-dihydro-2H-pyrrol-2-one?
You can request a quote for 5-(3-bromophenyl)-3-hydroxy-4-{[4-(propan-2-yloxy)phenyl]carbonyl}-1-(1,3-thiazol-2-yl)-1,5-dihydro-2H-pyrrol-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-(3-bromophenyl)-3-hydroxy-4-{[4-(propan-2-yloxy)phenyl]carbonyl}-1-(1,3-thiazol-2-yl)-1,5-dihydro-2H-pyrrol-2-one?
Yes, KEHONG BIO provides custom synthesis services for 5-(3-bromophenyl)-3-hydroxy-4-{[4-(propan-2-yloxy)phenyl]carbonyl}-1-(1,3-thiazol-2-yl)-1,5-dihydro-2H-pyrrol-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.