(E)-2-((4-benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide
TL;DR: (E)-2-((4-benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide (CAS 370868-90-9) is a chemical compound with molecular formula C25H24N6O3S and molecular weight 488.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[(4-benzyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(E)-(2,3-dimethoxyphenyl)methylideneamino]acetamide
Also Known As: (E)-2-((4-benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide, 2-[(4-benzyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(E)-(2,3-dimethoxyphenyl)methylideneamino]acetamide, 2-{[4-benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N'-[(E)-(2,3-dimethoxyphenyl)methylidene]acetohydrazide
| Molecular Formula | C25H24N6O3S |
|---|---|
| Molecular Weight | 488.16 g/mol |
| LogP | 3.648 |
| Topological Polar Surface Area | 103.52 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 10 |
| Exact Mass | 488.16306 |
| Heavy Atoms | 35 |
| Complexity | 1295.3223 |
Chemical Identifiers
| CAS Number | 370868-90-9 |
|---|---|
| SMILES | COC1=CC=CC(=C1OC)/C=N/NC(=O)CSC2=NN=C(N2CC3=CC=CC=C3)C4=CC=NC=C4 |
Product Overview
(E)-2-((4-benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide (CAS 370868-90-9), with molecular formula C25H24N6O3S and molecular weight 488.16 g/mol. IUPAC: 2-[(4-benzyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-N-[(E)-(2,3-dimethoxyphenyl)methylideneamino]acetamide.
Chemical Property Profile of (E)-2-((4-benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide
Property Insights of (E)-2-((4-benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide
The XLogP value of 3.648 indicates that (E)-2-((4-benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 103.52 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-2-((4-benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide. Following Lipinski's Rule of Five, (E)-2-((4-benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-2-((4-benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide?
The CAS number of (E)-2-((4-benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide is 370868-90-9.
What is the molecular formula of (E)-2-((4-benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide?
The molecular formula of (E)-2-((4-benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide is C25H24N6O3S.
What is the molecular weight of (E)-2-((4-benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide?
The molecular weight of (E)-2-((4-benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide is 488.16 g/mol.
Where can I buy (E)-2-((4-benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide?
You can request a quote for (E)-2-((4-benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-2-((4-benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide?
Yes, KEHONG BIO provides custom synthesis services for (E)-2-((4-benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.