A2851/0120306
TL;DR: A2851/0120306 (CAS 370854-70-9) is a chemical compound with molecular formula C22H22ClN3O2S and molecular weight 427.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5E)-2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(2-ethoxyphenyl)methylidene]-1,3-thiazol-4-one
Also Known As: A2851/0120306, (5E)-2-[4-(4-chlorophenyl)piperazin-1-yl]-5-(2-ethoxybenzylidene)-1,3-thiazol-4(5H)-one, (E)-2-(4-(4-chlorophenyl)piperazin-1-yl)-5-(2-ethoxybenzylidene)thiazol-4(5H)-one, (5E)-2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(2-ethoxyphenyl)methylidene]-1,3-thiazol-4-one, (5E)-2-[4-(4-CHLOROPHENYL)PIPERAZIN-1-YL]-5-[(2-ETHOXYPHENYL)METHYLIDENE]-4,5-DIHYDRO-1,3-THIAZOL-4-ONE
| Molecular Formula | C22H22ClN3O2S |
|---|---|
| Molecular Weight | 427.11 g/mol |
| LogP | 4.5312 |
| Topological Polar Surface Area | 45.14 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 427.11212 |
| Heavy Atoms | 29 |
| Complexity | 950.78467 |
Chemical Identifiers
| CAS Number | 370854-70-9 |
|---|---|
| SMILES | CCOC1=CC=CC=C1/C=C/2\C(=O)N=C(S2)N3CCN(CC3)C4=CC=C(C=C4)Cl |
Product Overview
A2851/0120306 (CAS 370854-70-9), with molecular formula C22H22ClN3O2S and molecular weight 427.11 g/mol. IUPAC: (5E)-2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(2-ethoxyphenyl)methylidene]-1,3-thiazol-4-one.
Chemical Property Profile of A2851/0120306
Property Insights of A2851/0120306
The XLogP value of 4.5312 indicates that A2851/0120306 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 45.14 Ų, A2851/0120306 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, A2851/0120306 has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of A2851/0120306?
The CAS number of A2851/0120306 is 370854-70-9.
What is the molecular formula of A2851/0120306?
The molecular formula of A2851/0120306 is C22H22ClN3O2S.
What is the molecular weight of A2851/0120306?
The molecular weight of A2851/0120306 is 427.11 g/mol.
Where can I buy A2851/0120306?
You can request a quote for A2851/0120306 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for A2851/0120306?
Yes, KEHONG BIO provides custom synthesis services for A2851/0120306 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.