![8-fluoro-4-(4-methylpiperazin-1-yl)-5H-pyrimido[5,4-b]indole structure](/static/products/370/370846-48-3.png)
8-fluoro-4-(4-methylpiperazin-1-yl)-5H-pyrimido[5,4-b]indole
TL;DR: 8-fluoro-4-(4-methylpiperazin-1-yl)-5H-pyrimido[5,4-b]indole (CAS 370846-48-3) is a chemical compound with molecular formula C15H16FN5 and molecular weight 285.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
8-fluoro-4-(4-methylpiperazin-1-yl)-5H-pyrimido[5,4-b]indole
Also Known As: 8-fluoro-4-(4-methylpiperazin-1-yl)-5H-pyrimido[5,4-b]indole, REGID_for_CID_659867
| Molecular Formula | C15H16FN5 |
|---|---|
| Molecular Weight | 285.14 g/mol |
| LogP | 2.1 |
| Topological Polar Surface Area | 48.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 1 |
| Exact Mass | 285.13898 |
| Heavy Atoms | 21 |
| Complexity | 373.0 |
Chemical Identifiers
| CAS Number | 370846-48-3 |
|---|---|
| SMILES | CN1CCN(CC1)C2=NC=NC3=C2NC4=C3C=C(C=C4)F |
| InChIKey | LEYHARBCQOPTMC-UHFFFAOYSA-N |
Product Overview
8-fluoro-4-(4-methylpiperazin-1-yl)-5H-pyrimido[5,4-b]indole (CAS 370846-48-3), with molecular formula C15H16FN5 and molecular weight 285.14 g/mol. IUPAC: 8-fluoro-4-(4-methylpiperazin-1-yl)-5H-pyrimido[5,4-b]indole.
Chemical Property Profile of 8-fluoro-4-(4-methylpiperazin-1-yl)-5H-pyrimido[5,4-b]indole
Property Insights of 8-fluoro-4-(4-methylpiperazin-1-yl)-5H-pyrimido[5,4-b]indole
The XLogP value of 2.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 8-fluoro-4-(4-methylpiperazin-1-yl)-5H-pyrimido[5,4-b]indole. With a topological polar surface area (TPSA) of 48.1 Ų, 8-fluoro-4-(4-methylpiperazin-1-yl)-5H-pyrimido[5,4-b]indole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 8-fluoro-4-(4-methylpiperazin-1-yl)-5H-pyrimido[5,4-b]indole has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8-fluoro-4-(4-methylpiperazin-1-yl)-5H-pyrimido[5,4-b]indole?
The CAS number of 8-fluoro-4-(4-methylpiperazin-1-yl)-5H-pyrimido[5,4-b]indole is 370846-48-3.
What is the molecular formula of 8-fluoro-4-(4-methylpiperazin-1-yl)-5H-pyrimido[5,4-b]indole?
The molecular formula of 8-fluoro-4-(4-methylpiperazin-1-yl)-5H-pyrimido[5,4-b]indole is C15H16FN5.
What is the molecular weight of 8-fluoro-4-(4-methylpiperazin-1-yl)-5H-pyrimido[5,4-b]indole?
The molecular weight of 8-fluoro-4-(4-methylpiperazin-1-yl)-5H-pyrimido[5,4-b]indole is 285.14 g/mol.
Where can I buy 8-fluoro-4-(4-methylpiperazin-1-yl)-5H-pyrimido[5,4-b]indole?
You can request a quote for 8-fluoro-4-(4-methylpiperazin-1-yl)-5H-pyrimido[5,4-b]indole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8-fluoro-4-(4-methylpiperazin-1-yl)-5H-pyrimido[5,4-b]indole?
Yes, KEHONG BIO provides custom synthesis services for 8-fluoro-4-(4-methylpiperazin-1-yl)-5H-pyrimido[5,4-b]indole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.