AE-848/15115132
TL;DR: AE-848/15115132 (CAS 370843-93-9) is a chemical compound with molecular formula C18H14FN3O2S2 and molecular weight 387.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[(5-cyano-2-oxo-4-thiophen-2-yl-3,4-dihydro-1H-pyridin-6-yl)sulfanyl]-N-(4-fluorophenyl)acetamide
Also Known As: AE-848/15115132, 2-{[3-cyano-6-oxo-4-(thiophen-2-yl)-1,4,5,6-tetrahydropyridin-2-yl]sulfanyl}-N-(4-fluorophenyl)acetamide, 2-[(5-cyano-2-oxo-4-thiophen-2-yl-3,4-dihydro-1H-pyridin-6-yl)sulfanyl]-N-(4-fluorophenyl)acetamide, 2-((3-cyano-6-oxo-4-(thiophen-2-yl)-1,4,5,6-tetrahydropyridin-2-yl)thio)-N-(4-fluorophenyl)acetamide, 2-{[3-cyano-6-hydroxy-4-(thiophen-2-yl)-4,5-dihydropyridin-2-yl]sulfanyl}-N-(4-fluorophenyl)acetamide
| Molecular Formula | C18H14FN3O2S2 |
|---|---|
| Molecular Weight | 387.05 g/mol |
| LogP | 3.59778 |
| Topological Polar Surface Area | 81.99 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 387.05115 |
| Heavy Atoms | 26 |
| Complexity | 886.1601 |
Chemical Identifiers
| CAS Number | 370843-93-9 |
|---|---|
| SMILES | C1C(C(=C(NC1=O)SCC(=O)NC2=CC=C(C=C2)F)C#N)C3=CC=CS3 |
Product Overview
AE-848/15115132 (CAS 370843-93-9), with molecular formula C18H14FN3O2S2 and molecular weight 387.05 g/mol. IUPAC: 2-[(5-cyano-2-oxo-4-thiophen-2-yl-3,4-dihydro-1H-pyridin-6-yl)sulfanyl]-N-(4-fluorophenyl)acetamide.
Chemical Property Profile of AE-848/15115132
Property Insights of AE-848/15115132
The XLogP value of 3.59778 indicates that AE-848/15115132 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 81.99 Ų falls within the moderate polarity range, balancing permeability and solubility for AE-848/15115132. Following Lipinski's Rule of Five, AE-848/15115132 has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AE-848/15115132?
The CAS number of AE-848/15115132 is 370843-93-9.
What is the molecular formula of AE-848/15115132?
The molecular formula of AE-848/15115132 is C18H14FN3O2S2.
What is the molecular weight of AE-848/15115132?
The molecular weight of AE-848/15115132 is 387.05 g/mol.
Where can I buy AE-848/15115132?
You can request a quote for AE-848/15115132 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AE-848/15115132?
Yes, KEHONG BIO provides custom synthesis services for AE-848/15115132 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.