(E)-3-(4-Methoxy-phenyl)-N-(4-pyridin-2-yl-piperazine-1-carbothioyl)-acrylamide
TL;DR: (E)-3-(4-Methoxy-phenyl)-N-(4-pyridin-2-yl-piperazine-1-carbothioyl)-acrylamide (CAS 370574-97-3) is a chemical compound with molecular formula C20H22N4O2S and molecular weight 382.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-3-(4-methoxyphenyl)-N-(4-pyridin-2-ylpiperazine-1-carbothioyl)prop-2-enamide
Also Known As: (E)-3-(4-Methoxy-phenyl)-N-(4-pyridin-2-yl-piperazine-1-carbothioyl)-acrylamide, (E)-3-(4-methoxyphenyl)-N-(4-pyridin-2-ylpiperazine-1-carbothioyl)prop-2-enamide, (2E)-3-(4-methoxyphenyl)-N-{[4-(pyridin-2-yl)piperazin-1-yl]carbonothioyl}prop-2-enamide, (E)-3-(4-methoxyphenyl)-N-(4-(pyridin-2-yl)piperazine-1-carbonothioyl)acrylamide, 3-(4-methoxyphenyl)-N-(4-pyridin-2-ylpiperazine-1-carbothioyl)prop-2-enamide
| Molecular Formula | C20H22N4O2S |
|---|---|
| Molecular Weight | 382.15 g/mol |
| LogP | 2.3267 |
| Topological Polar Surface Area | 57.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 382.14636 |
| Heavy Atoms | 27 |
| Complexity | 800.4912 |
Chemical Identifiers
| CAS Number | 370574-97-3 |
|---|---|
| SMILES | COC1=CC=C(C=C1)/C=C/C(=O)NC(=S)N2CCN(CC2)C3=CC=CC=N3 |
Product Overview
(E)-3-(4-Methoxy-phenyl)-N-(4-pyridin-2-yl-piperazine-1-carbothioyl)-acrylamide (CAS 370574-97-3), with molecular formula C20H22N4O2S and molecular weight 382.15 g/mol. IUPAC: (E)-3-(4-methoxyphenyl)-N-(4-pyridin-2-ylpiperazine-1-carbothioyl)prop-2-enamide.
Chemical Property Profile of (E)-3-(4-Methoxy-phenyl)-N-(4-pyridin-2-yl-piperazine-1-carbothioyl)-acrylamide
Property Insights of (E)-3-(4-Methoxy-phenyl)-N-(4-pyridin-2-yl-piperazine-1-carbothioyl)-acrylamide
The XLogP value of 2.3267 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (E)-3-(4-Methoxy-phenyl)-N-(4-pyridin-2-yl-piperazine-1-carbothioyl)-acrylamide. With a topological polar surface area (TPSA) of 57.7 Ų, (E)-3-(4-Methoxy-phenyl)-N-(4-pyridin-2-yl-piperazine-1-carbothioyl)-acrylamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-3-(4-Methoxy-phenyl)-N-(4-pyridin-2-yl-piperazine-1-carbothioyl)-acrylamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-3-(4-Methoxy-phenyl)-N-(4-pyridin-2-yl-piperazine-1-carbothioyl)-acrylamide?
The CAS number of (E)-3-(4-Methoxy-phenyl)-N-(4-pyridin-2-yl-piperazine-1-carbothioyl)-acrylamide is 370574-97-3.
What is the molecular formula of (E)-3-(4-Methoxy-phenyl)-N-(4-pyridin-2-yl-piperazine-1-carbothioyl)-acrylamide?
The molecular formula of (E)-3-(4-Methoxy-phenyl)-N-(4-pyridin-2-yl-piperazine-1-carbothioyl)-acrylamide is C20H22N4O2S.
What is the molecular weight of (E)-3-(4-Methoxy-phenyl)-N-(4-pyridin-2-yl-piperazine-1-carbothioyl)-acrylamide?
The molecular weight of (E)-3-(4-Methoxy-phenyl)-N-(4-pyridin-2-yl-piperazine-1-carbothioyl)-acrylamide is 382.15 g/mol.
Where can I buy (E)-3-(4-Methoxy-phenyl)-N-(4-pyridin-2-yl-piperazine-1-carbothioyl)-acrylamide?
You can request a quote for (E)-3-(4-Methoxy-phenyl)-N-(4-pyridin-2-yl-piperazine-1-carbothioyl)-acrylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-3-(4-Methoxy-phenyl)-N-(4-pyridin-2-yl-piperazine-1-carbothioyl)-acrylamide?
Yes, KEHONG BIO provides custom synthesis services for (E)-3-(4-Methoxy-phenyl)-N-(4-pyridin-2-yl-piperazine-1-carbothioyl)-acrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.