(Z)-4-hydroxy-4-(3-methylphenyl)-2-oxo-N-(1,3-thiazol-2-yl)but-3-enamide
TL;DR: (Z)-4-hydroxy-4-(3-methylphenyl)-2-oxo-N-(1,3-thiazol-2-yl)but-3-enamide (CAS 370074-71-8) is a chemical compound with molecular formula C14H12N2O3S and molecular weight 288.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(Z)-4-hydroxy-4-(3-methylphenyl)-2-oxo-N-(1,3-thiazol-2-yl)but-3-enamide
| Molecular Formula | C14H12N2O3S |
|---|---|
| Molecular Weight | 288.06 g/mol |
| LogP | 2.55822 |
| Topological Polar Surface Area | 79.29 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 288.05685 |
| Heavy Atoms | 20 |
| Complexity | 662.81836 |
Chemical Identifiers
| CAS Number | 370074-71-8 |
|---|---|
| SMILES | CC1=CC(=CC=C1)/C(=C/C(=O)C(=O)NC2=NC=CS2)/O |
Product Overview
(Z)-4-hydroxy-4-(3-methylphenyl)-2-oxo-N-(1,3-thiazol-2-yl)but-3-enamide (CAS 370074-71-8), with molecular formula C14H12N2O3S and molecular weight 288.06 g/mol. IUPAC: (Z)-4-hydroxy-4-(3-methylphenyl)-2-oxo-N-(1,3-thiazol-2-yl)but-3-enamide.
Chemical Property Profile of (Z)-4-hydroxy-4-(3-methylphenyl)-2-oxo-N-(1,3-thiazol-2-yl)but-3-enamide
Property Insights of (Z)-4-hydroxy-4-(3-methylphenyl)-2-oxo-N-(1,3-thiazol-2-yl)but-3-enamide
The XLogP value of 2.55822 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (Z)-4-hydroxy-4-(3-methylphenyl)-2-oxo-N-(1,3-thiazol-2-yl)but-3-enamide. The TPSA of 79.29 Ų falls within the moderate polarity range, balancing permeability and solubility for (Z)-4-hydroxy-4-(3-methylphenyl)-2-oxo-N-(1,3-thiazol-2-yl)but-3-enamide. Following Lipinski's Rule of Five, (Z)-4-hydroxy-4-(3-methylphenyl)-2-oxo-N-(1,3-thiazol-2-yl)but-3-enamide has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (Z)-4-hydroxy-4-(3-methylphenyl)-2-oxo-N-(1,3-thiazol-2-yl)but-3-enamide?
The CAS number of (Z)-4-hydroxy-4-(3-methylphenyl)-2-oxo-N-(1,3-thiazol-2-yl)but-3-enamide is 370074-71-8.
What is the molecular formula of (Z)-4-hydroxy-4-(3-methylphenyl)-2-oxo-N-(1,3-thiazol-2-yl)but-3-enamide?
The molecular formula of (Z)-4-hydroxy-4-(3-methylphenyl)-2-oxo-N-(1,3-thiazol-2-yl)but-3-enamide is C14H12N2O3S.
What is the molecular weight of (Z)-4-hydroxy-4-(3-methylphenyl)-2-oxo-N-(1,3-thiazol-2-yl)but-3-enamide?
The molecular weight of (Z)-4-hydroxy-4-(3-methylphenyl)-2-oxo-N-(1,3-thiazol-2-yl)but-3-enamide is 288.06 g/mol.
Where can I buy (Z)-4-hydroxy-4-(3-methylphenyl)-2-oxo-N-(1,3-thiazol-2-yl)but-3-enamide?
You can request a quote for (Z)-4-hydroxy-4-(3-methylphenyl)-2-oxo-N-(1,3-thiazol-2-yl)but-3-enamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (Z)-4-hydroxy-4-(3-methylphenyl)-2-oxo-N-(1,3-thiazol-2-yl)but-3-enamide?
Yes, KEHONG BIO provides custom synthesis services for (Z)-4-hydroxy-4-(3-methylphenyl)-2-oxo-N-(1,3-thiazol-2-yl)but-3-enamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.