(E)-5-(2-(benzyloxy)benzylidene)-2-(4-(4-chlorophenyl)piperazin-1-yl)thiazol-4(5H)-one
TL;DR: (E)-5-(2-(benzyloxy)benzylidene)-2-(4-(4-chlorophenyl)piperazin-1-yl)thiazol-4(5H)-one (CAS 369397-55-7) is a chemical compound with molecular formula C27H24ClN3O2S and molecular weight 489.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5E)-2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(2-phenylmethoxyphenyl)methylidene]-1,3-thiazol-4-one
Also Known As: (E)-5-(2-(benzyloxy)benzylidene)-2-(4-(4-chlorophenyl)piperazin-1-yl)thiazol-4(5H)-one, (5E)-2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(2-phenylmethoxyphenyl)methylidene]-1,3-thiazol-4-one, (5E)-5-[2-(benzyloxy)benzylidene]-2-[4-(4-chlorophenyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one, 2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(2-phenylmethoxyphenyl)methylidene]-1,3-thiazol-4-one
| Molecular Formula | C27H24ClN3O2S |
|---|---|
| Molecular Weight | 489.13 g/mol |
| LogP | 5.7115 |
| Topological Polar Surface Area | 45.14 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 489.12778 |
| Heavy Atoms | 34 |
| Complexity | 1220.1373 |
Chemical Identifiers
| CAS Number | 369397-55-7 |
|---|---|
| SMILES | C1CN(CCN1C2=CC=C(C=C2)Cl)C3=NC(=O)/C(=C\C4=CC=CC=C4OCC5=CC=CC=C5)/S3 |
Product Overview
(E)-5-(2-(benzyloxy)benzylidene)-2-(4-(4-chlorophenyl)piperazin-1-yl)thiazol-4(5H)-one (CAS 369397-55-7), with molecular formula C27H24ClN3O2S and molecular weight 489.13 g/mol. IUPAC: (5E)-2-[4-(4-chlorophenyl)piperazin-1-yl]-5-[(2-phenylmethoxyphenyl)methylidene]-1,3-thiazol-4-one.
Chemical Property Profile of (E)-5-(2-(benzyloxy)benzylidene)-2-(4-(4-chlorophenyl)piperazin-1-yl)thiazol-4(5H)-one
Property Insights of (E)-5-(2-(benzyloxy)benzylidene)-2-(4-(4-chlorophenyl)piperazin-1-yl)thiazol-4(5H)-one
The XLogP value of 5.7115 indicates that (E)-5-(2-(benzyloxy)benzylidene)-2-(4-(4-chlorophenyl)piperazin-1-yl)thiazol-4(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 45.14 Ų, (E)-5-(2-(benzyloxy)benzylidene)-2-(4-(4-chlorophenyl)piperazin-1-yl)thiazol-4(5H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-5-(2-(benzyloxy)benzylidene)-2-(4-(4-chlorophenyl)piperazin-1-yl)thiazol-4(5H)-one has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-5-(2-(benzyloxy)benzylidene)-2-(4-(4-chlorophenyl)piperazin-1-yl)thiazol-4(5H)-one?
The CAS number of (E)-5-(2-(benzyloxy)benzylidene)-2-(4-(4-chlorophenyl)piperazin-1-yl)thiazol-4(5H)-one is 369397-55-7.
What is the molecular formula of (E)-5-(2-(benzyloxy)benzylidene)-2-(4-(4-chlorophenyl)piperazin-1-yl)thiazol-4(5H)-one?
The molecular formula of (E)-5-(2-(benzyloxy)benzylidene)-2-(4-(4-chlorophenyl)piperazin-1-yl)thiazol-4(5H)-one is C27H24ClN3O2S.
What is the molecular weight of (E)-5-(2-(benzyloxy)benzylidene)-2-(4-(4-chlorophenyl)piperazin-1-yl)thiazol-4(5H)-one?
The molecular weight of (E)-5-(2-(benzyloxy)benzylidene)-2-(4-(4-chlorophenyl)piperazin-1-yl)thiazol-4(5H)-one is 489.13 g/mol.
Where can I buy (E)-5-(2-(benzyloxy)benzylidene)-2-(4-(4-chlorophenyl)piperazin-1-yl)thiazol-4(5H)-one?
You can request a quote for (E)-5-(2-(benzyloxy)benzylidene)-2-(4-(4-chlorophenyl)piperazin-1-yl)thiazol-4(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-5-(2-(benzyloxy)benzylidene)-2-(4-(4-chlorophenyl)piperazin-1-yl)thiazol-4(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for (E)-5-(2-(benzyloxy)benzylidene)-2-(4-(4-chlorophenyl)piperazin-1-yl)thiazol-4(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.