![(5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one structure](/static/products/369/369396-40-7.png)
(5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one
TL;DR: (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one (CAS 369396-40-7) is a chemical compound with molecular formula C18H22N2O2S and molecular weight 330.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5E)-2-piperidin-1-yl-5-[(2-propan-2-yloxyphenyl)methylidene]-1,3-thiazol-4-one
Also Known As: (E)-5-(2-isopropoxybenzylidene)-2-(piperidin-1-yl)thiazol-4(5H)-one, (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one, (5E)-2-piperidin-1-yl-5-[(2-propan-2-yloxyphenyl)methylidene]-1,3-thiazol-4-one
| Molecular Formula | C18H22N2O2S |
|---|---|
| Molecular Weight | 330.14 g/mol |
| LogP | 3.93 |
| Topological Polar Surface Area | 41.9 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 330.1402 |
| Heavy Atoms | 23 |
| Complexity | 646.1766 |
Chemical Identifiers
| CAS Number | 369396-40-7 |
|---|---|
| SMILES | CC(C)OC1=CC=CC=C1/C=C/2\C(=O)N=C(S2)N3CCCCC3 |
Product Overview
(5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one (CAS 369396-40-7), with molecular formula C18H22N2O2S and molecular weight 330.14 g/mol. IUPAC: (5E)-2-piperidin-1-yl-5-[(2-propan-2-yloxyphenyl)methylidene]-1,3-thiazol-4-one.
Chemical Property Profile of (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one
Property Insights of (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one
The XLogP value of 3.93 indicates that (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.9 Ų, (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one?
The CAS number of (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one is 369396-40-7.
What is the molecular formula of (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one?
The molecular formula of (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one is C18H22N2O2S.
What is the molecular weight of (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one?
The molecular weight of (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one is 330.14 g/mol.
Where can I buy (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one?
You can request a quote for (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for (5E)-2-(piperidin-1-yl)-5-[2-(propan-2-yloxy)benzylidene]-1,3-thiazol-4(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.