8-chloro-3-ethyl-2-methylquinoline-4(1H)-thione
TL;DR: 8-chloro-3-ethyl-2-methylquinoline-4(1H)-thione (CAS 369394-97-8) is a chemical compound with molecular formula C12H12ClNS and molecular weight 237.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
8-chloro-3-ethyl-2-methyl-1H-quinoline-4-thione
Also Known As: 8-chloro-3-ethyl-2-methyl-1H-quinoline-4-thione, 8-chloro-3-ethyl-2-methylquinoline-4(1H)-thione, 8-CHLORO-3-ETHYL-2-METHYLQUINOLINE-4-THIOL
| Molecular Formula | C12H12ClNS |
|---|---|
| Molecular Weight | 237.04 g/mol |
| LogP | 4.42161 |
| Topological Polar Surface Area | 15.79 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 237.0379 |
| Heavy Atoms | 15 |
| Complexity | 571.5792 |
Chemical Identifiers
| CAS Number | 369394-97-8 |
|---|---|
| SMILES | CCC1=C(NC2=C(C1=S)C=CC=C2Cl)C |
Product Overview
8-chloro-3-ethyl-2-methylquinoline-4(1H)-thione (CAS 369394-97-8), with molecular formula C12H12ClNS and molecular weight 237.04 g/mol. IUPAC: 8-chloro-3-ethyl-2-methyl-1H-quinoline-4-thione.
Chemical Property Profile of 8-chloro-3-ethyl-2-methylquinoline-4(1H)-thione
Property Insights of 8-chloro-3-ethyl-2-methylquinoline-4(1H)-thione
The XLogP value of 4.42161 indicates that 8-chloro-3-ethyl-2-methylquinoline-4(1H)-thione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 15.79 Ų, 8-chloro-3-ethyl-2-methylquinoline-4(1H)-thione exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 8-chloro-3-ethyl-2-methylquinoline-4(1H)-thione has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8-chloro-3-ethyl-2-methylquinoline-4(1H)-thione?
The CAS number of 8-chloro-3-ethyl-2-methylquinoline-4(1H)-thione is 369394-97-8.
What is the molecular formula of 8-chloro-3-ethyl-2-methylquinoline-4(1H)-thione?
The molecular formula of 8-chloro-3-ethyl-2-methylquinoline-4(1H)-thione is C12H12ClNS.
What is the molecular weight of 8-chloro-3-ethyl-2-methylquinoline-4(1H)-thione?
The molecular weight of 8-chloro-3-ethyl-2-methylquinoline-4(1H)-thione is 237.04 g/mol.
Where can I buy 8-chloro-3-ethyl-2-methylquinoline-4(1H)-thione?
You can request a quote for 8-chloro-3-ethyl-2-methylquinoline-4(1H)-thione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8-chloro-3-ethyl-2-methylquinoline-4(1H)-thione?
Yes, KEHONG BIO provides custom synthesis services for 8-chloro-3-ethyl-2-methylquinoline-4(1H)-thione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.