(E)-N'-(3-((2-chloro-5-fluoropyrimidin-4-yl)oxy)benzylidene)-3-iodobenzohydrazide structure

(E)-N'-(3-((2-chloro-5-fluoropyrimidin-4-yl)oxy)benzylidene)-3-iodobenzohydrazide

TL;DR: (E)-N'-(3-((2-chloro-5-fluoropyrimidin-4-yl)oxy)benzylidene)-3-iodobenzohydrazide (CAS 369393-48-6) is a chemical compound with molecular formula C18H11ClFIN4O2 and molecular weight 495.96 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-[(E)-[3-(2-chloro-5-fluoropyrimidin-4-yl)oxyphenyl]methylideneamino]-3-iodobenzamide

Also Known As: (E)-N'-(3-((2-chloro-5-fluoropyrimidin-4-yl)oxy)benzylidene)-3-iodobenzohydrazide, N'-[(E)-{3-[(2-chloro-5-fluoropyrimidin-4-yl)oxy]phenyl}methylidene]-3-iodobenzohydrazide, N-[(E)-[3-(2-chloro-5-fluoropyrimidin-4-yl)oxyphenyl]methylideneamino]-3-iodobenzamide, N-[[3-(2-chloro-5-fluoro-pyrimidin-4-yl)oxyphenyl]methylideneamino]-3-iodo-benzamide, N-{(1E)-2-[3-(2-chloro-5-fluoropyrimidin-4-yloxy)phenyl]-1-azavinyl}(3-iodophe nyl)carboxamide

CAS: 369393-48-6
Molecular Formula C18H11ClFIN4O2
Molecular Weight 495.96 g/mol
LogP 4.4299
Topological Polar Surface Area 76.47 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 5
Rotatable Bonds 5
Exact Mass 495.95993
Heavy Atoms 27
Complexity 1016.15674

Chemical Identifiers

CAS Number 369393-48-6
SMILES C1=CC(=CC(=C1)OC2=NC(=NC=C2F)Cl)/C=N/NC(=O)C3=CC(=CC=C3)I

Product Overview

(E)-N'-(3-((2-chloro-5-fluoropyrimidin-4-yl)oxy)benzylidene)-3-iodobenzohydrazide (CAS 369393-48-6), with molecular formula C18H11ClFIN4O2 and molecular weight 495.96 g/mol. IUPAC: N-[(E)-[3-(2-chloro-5-fluoropyrimidin-4-yl)oxyphenyl]methylideneamino]-3-iodobenzamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of (E)-N'-(3-((2-chloro-5-fluoropyrimidin-4-yl)oxy)benzylidene)-3-iodobenzohydrazide

XLogP
4.4299
TPSA (Topological Polar Surface Area)
76.47
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
5
Rotatable Bonds
5
Heavy Atoms
27
Complexity
1016.15674
Exact Mass
495.95993
Monoisotopic Mass
495.95993
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of (E)-N'-(3-((2-chloro-5-fluoropyrimidin-4-yl)oxy)benzylidene)-3-iodobenzohydrazide

The XLogP value of 4.4299 indicates that (E)-N'-(3-((2-chloro-5-fluoropyrimidin-4-yl)oxy)benzylidene)-3-iodobenzohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 76.47 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-N'-(3-((2-chloro-5-fluoropyrimidin-4-yl)oxy)benzylidene)-3-iodobenzohydrazide. Following Lipinski's Rule of Five, (E)-N'-(3-((2-chloro-5-fluoropyrimidin-4-yl)oxy)benzylidene)-3-iodobenzohydrazide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of (E)-N'-(3-((2-chloro-5-fluoropyrimidin-4-yl)oxy)benzylidene)-3-iodobenzohydrazide?

The CAS number of (E)-N'-(3-((2-chloro-5-fluoropyrimidin-4-yl)oxy)benzylidene)-3-iodobenzohydrazide is 369393-48-6.

What is the molecular formula of (E)-N'-(3-((2-chloro-5-fluoropyrimidin-4-yl)oxy)benzylidene)-3-iodobenzohydrazide?

The molecular formula of (E)-N'-(3-((2-chloro-5-fluoropyrimidin-4-yl)oxy)benzylidene)-3-iodobenzohydrazide is C18H11ClFIN4O2.

What is the molecular weight of (E)-N'-(3-((2-chloro-5-fluoropyrimidin-4-yl)oxy)benzylidene)-3-iodobenzohydrazide?

The molecular weight of (E)-N'-(3-((2-chloro-5-fluoropyrimidin-4-yl)oxy)benzylidene)-3-iodobenzohydrazide is 495.96 g/mol.

Where can I buy (E)-N'-(3-((2-chloro-5-fluoropyrimidin-4-yl)oxy)benzylidene)-3-iodobenzohydrazide?

You can request a quote for (E)-N'-(3-((2-chloro-5-fluoropyrimidin-4-yl)oxy)benzylidene)-3-iodobenzohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for (E)-N'-(3-((2-chloro-5-fluoropyrimidin-4-yl)oxy)benzylidene)-3-iodobenzohydrazide?

Yes, KEHONG BIO provides custom synthesis services for (E)-N'-(3-((2-chloro-5-fluoropyrimidin-4-yl)oxy)benzylidene)-3-iodobenzohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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