AF-399/40827445 structure

AF-399/40827445

TL;DR: AF-399/40827445 (CAS 367907-01-5) is a chemical compound with molecular formula C25H22N6O2 and molecular weight 438.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

5-methyl-7-(4-phenylmethoxyphenyl)-N-pyridin-3-yl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide

Also Known As: AF-399/40827445, 7-(4-(benzyloxy)phenyl)-5-methyl-N-(pyridin-3-yl)-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide, F1038-0591, 7-[4-(benzyloxy)phenyl]-5-methyl-N-(pyridin-3-yl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide, 5-methyl-7-(4-phenylmethoxyphenyl)-N-pyridin-3-yl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide

CAS: 367907-01-5
Molecular Formula C25H22N6O2
Molecular Weight 438.18 g/mol
LogP 4.1797
Topological Polar Surface Area 93.96 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 6
Rotatable Bonds 6
Exact Mass 438.18042
Heavy Atoms 33
Complexity 1283.5037

Chemical Identifiers

CAS Number 367907-01-5
SMILES CC1=C(C(N2C(=NC=N2)N1)C3=CC=C(C=C3)OCC4=CC=CC=C4)C(=O)NC5=CN=CC=C5

Product Overview

AF-399/40827445 (CAS 367907-01-5), with molecular formula C25H22N6O2 and molecular weight 438.18 g/mol. IUPAC: 5-methyl-7-(4-phenylmethoxyphenyl)-N-pyridin-3-yl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of AF-399/40827445

XLogP
4.1797
TPSA (Topological Polar Surface Area)
93.96
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
6
Rotatable Bonds
6
Heavy Atoms
33
Complexity
1283.5037
Exact Mass
438.18042
Monoisotopic Mass
438.18042
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of AF-399/40827445

The XLogP value of 4.1797 indicates that AF-399/40827445 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 93.96 Ų falls within the moderate polarity range, balancing permeability and solubility for AF-399/40827445. Following Lipinski's Rule of Five, AF-399/40827445 has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of AF-399/40827445?

The CAS number of AF-399/40827445 is 367907-01-5.

What is the molecular formula of AF-399/40827445?

The molecular formula of AF-399/40827445 is C25H22N6O2.

What is the molecular weight of AF-399/40827445?

The molecular weight of AF-399/40827445 is 438.18 g/mol.

Where can I buy AF-399/40827445?

You can request a quote for AF-399/40827445 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for AF-399/40827445?

Yes, KEHONG BIO provides custom synthesis services for AF-399/40827445 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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