DPC 681 structure

DPC 681

TL;DR: DPC 681 (CAS 367281-49-0) is a chemical compound with molecular formula C35H48FN5O5S and molecular weight 669.34 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2S)-N-[(2S,3R)-4-[(3-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]-2-[[2-[(3-fluorophenyl)methylamino]acetyl]amino]-3,3-dimethylbutanamide

Also Known As: DPC 681, BRD-K37087535-001-01-1, L-Valinamide, N-[(3-fluorophenyl)methyl]glycyl-N1-[(1S,2R)-3-[[(3-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-3-methyl-, (2S)-N-[(2S,3R)-4-[(3-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]-2-[[2-[(3-fluorophenyl)methylamino]acetyl]amino]-3,3-dimethylbutanamide, (2S)-N-[(1S,2R)-3-[(3-aminophenyl)sulfonyl-isobutyl-amino]-1-benzyl-2-hydroxy-propyl]-2-[[2-[(3-fluorophenyl)methylamino]acetyl]amino]-3,3-dimethyl-butanamide

CAS: 367281-49-0
Molecular Formula C35H48FN5O5S
Molecular Weight 669.34 g/mol
LogP 4.7
Topological Polar Surface Area 162.0 Ų
Hydrogen Bond Donors 5
Hydrogen Bond Acceptors 9
Rotatable Bonds 17
Exact Mass 669.336
Heavy Atoms 47
Complexity 1080.0

Chemical Identifiers

CAS Number 367281-49-0
SMILES CC(C)CN(C[C@H]([C@H](CC1=CC=CC=C1)NC(=O)[C@H](C(C)(C)C)NC(=O)CNCC2=CC(=CC=C2)F)O)S(=O)(=O)C3=CC=CC(=C3)N
InChIKey PNIFFZXGBAYVMQ-RKKDRKJOSA-N

Product Overview

DPC 681 (CAS 367281-49-0), with molecular formula C35H48FN5O5S and molecular weight 669.34 g/mol. IUPAC: (2S)-N-[(2S,3R)-4-[(3-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]-2-[[2-[(3-fluorophenyl)methylamino]acetyl]amino]-3,3-dimethylbutanamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of DPC 681

XLogP
4.7
TPSA (Topological Polar Surface Area)
162.0
Hydrogen Bond Donors
5
Hydrogen Bond Acceptors
9
Rotatable Bonds
17
Heavy Atoms
47
Complexity
1080.0
Exact Mass
669.336
Monoisotopic Mass
669.336
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of DPC 681

The XLogP value of 4.7 indicates that DPC 681 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 162.0 Ų indicates high polarity, suggesting DPC 681 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, DPC 681 has 5 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of DPC 681?

The CAS number of DPC 681 is 367281-49-0.

What is the molecular formula of DPC 681?

The molecular formula of DPC 681 is C35H48FN5O5S.

What is the molecular weight of DPC 681?

The molecular weight of DPC 681 is 669.34 g/mol.

Where can I buy DPC 681?

You can request a quote for DPC 681 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for DPC 681?

Yes, KEHONG BIO provides custom synthesis services for DPC 681 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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