N-Trifluoroacetylprolyl chloride
TL;DR: N-Trifluoroacetylprolyl chloride (CAS 36724-68-2) is a chemical compound with molecular formula C7H7ClF3NO2 and molecular weight 229.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-1-(2,2,2-trifluoroacetyl)pyrrolidine-2-carbonyl chloride
Also Known As: NTPC, N-Trifluoroacetylprolyl chloride, .TPC, N-Trifluoroacetyl-L-proline chloride, trifluoroacetyl-l-prolyl chloride
| Molecular Formula | C7H7ClF3NO2 |
|---|---|
| Molecular Weight | 229.01 g/mol |
| LogP | 1.3051 |
| Topological Polar Surface Area | 37.38 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 229.01173 |
| Heavy Atoms | 14 |
| Complexity | 266.15076 |
Chemical Identifiers
| CAS Number | 36724-68-2 |
|---|---|
| SMILES | C1C[C@H](N(C1)C(=O)C(F)(F)F)C(=O)Cl |
Product Overview
N-Trifluoroacetylprolyl chloride (CAS 36724-68-2), with molecular formula C7H7ClF3NO2 and molecular weight 229.01 g/mol. IUPAC: (2S)-1-(2,2,2-trifluoroacetyl)pyrrolidine-2-carbonyl chloride.
Chemical Property Profile of N-Trifluoroacetylprolyl chloride
Property Insights of N-Trifluoroacetylprolyl chloride
The XLogP value of 1.3051 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-Trifluoroacetylprolyl chloride. With a topological polar surface area (TPSA) of 37.38 Ų, N-Trifluoroacetylprolyl chloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-Trifluoroacetylprolyl chloride has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-Trifluoroacetylprolyl chloride?
The CAS number of N-Trifluoroacetylprolyl chloride is 36724-68-2.
What is the molecular formula of N-Trifluoroacetylprolyl chloride?
The molecular formula of N-Trifluoroacetylprolyl chloride is C7H7ClF3NO2.
What is the molecular weight of N-Trifluoroacetylprolyl chloride?
The molecular weight of N-Trifluoroacetylprolyl chloride is 229.01 g/mol.
Where can I buy N-Trifluoroacetylprolyl chloride?
You can request a quote for N-Trifluoroacetylprolyl chloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-Trifluoroacetylprolyl chloride?
Yes, KEHONG BIO provides custom synthesis services for N-Trifluoroacetylprolyl chloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.