5-Amino-2-(trifluoromethyl)benzimidazole
TL;DR: 5-Amino-2-(trifluoromethyl)benzimidazole (CAS 3671-66-7) is a chemical compound with molecular formula C8H6F3N3 and molecular weight 201.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(trifluoromethyl)-3H-benzimidazol-5-amine
Also Known As: 5-Amino-2-(trifluoromethyl)benzimidazole, 2-(Trifluoromethyl)-1H-benzo[d]imidazol-5-amine, ChemDiv3_006760, 1-Bromo-2,4-dichlorobenzene, 2-(trifluoromethyl)-3H-benzimidazol-5-amine
| Molecular Formula | C8H6F3N3 |
|---|---|
| Molecular Weight | 201.05 g/mol |
| LogP | 2.2 |
| Topological Polar Surface Area | 54.7 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 0 |
| Exact Mass | 201.05138 |
| Heavy Atoms | 14 |
| Complexity | 218.0 |
Chemical Identifiers
| CAS Number | 3671-66-7 |
|---|---|
| SMILES | C1=CC2=C(C=C1N)NC(=N2)C(F)(F)F |
| InChIKey | CKEKFQLHCAZGSP-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
5-Amino-2-(trifluoromethyl)benzimidazole (CAS 3671-66-7), with molecular formula C8H6F3N3 and molecular weight 201.05 g/mol. IUPAC: 2-(trifluoromethyl)-3H-benzimidazol-5-amine.
Chemical Property Profile of 5-Amino-2-(trifluoromethyl)benzimidazole
Property Insights of 5-Amino-2-(trifluoromethyl)benzimidazole
The XLogP value of 2.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5-Amino-2-(trifluoromethyl)benzimidazole. With a topological polar surface area (TPSA) of 54.7 Ų, 5-Amino-2-(trifluoromethyl)benzimidazole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-Amino-2-(trifluoromethyl)benzimidazole has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-Amino-2-(trifluoromethyl)benzimidazole?
The CAS number of 5-Amino-2-(trifluoromethyl)benzimidazole is 3671-66-7.
What is the molecular formula of 5-Amino-2-(trifluoromethyl)benzimidazole?
The molecular formula of 5-Amino-2-(trifluoromethyl)benzimidazole is C8H6F3N3.
What is the molecular weight of 5-Amino-2-(trifluoromethyl)benzimidazole?
The molecular weight of 5-Amino-2-(trifluoromethyl)benzimidazole is 201.05 g/mol.
Where can I buy 5-Amino-2-(trifluoromethyl)benzimidazole?
You can request a quote for 5-Amino-2-(trifluoromethyl)benzimidazole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-Amino-2-(trifluoromethyl)benzimidazole?
Yes, KEHONG BIO provides custom synthesis services for 5-Amino-2-(trifluoromethyl)benzimidazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.