API-1(NSC 177223)
TL;DR: API-1(NSC 177223) (CAS 36707-00-3) is a chemical compound with molecular formula C13H15N5O6 and molecular weight 337.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-amino-8-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-oxopyrido[2,3-d]pyrimidine-6-carboxamide
Also Known As: API-1(NSC 177223), API-1(NSC 177223)?, 4-amino-8-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-oxopyrido[2,3-d]pyrimidine-6-carboxamide, 4-AMINO-8-[(2R,3R,4S,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-5-OXOPYRIDO[2,3-D]PYRIMIDINE-6-CARBOXAMIDE, 4-Amino-5-oxo-8-pentofuranosyl-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide
| Molecular Formula | C13H15N5O6 |
|---|---|
| Molecular Weight | 337.10 g/mol |
| LogP | -1.9 |
| Topological Polar Surface Area | 185.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 3 |
| Exact Mass | 337.10223 |
| Heavy Atoms | 24 |
| Complexity | 571.0 |
Chemical Identifiers
| CAS Number | 36707-00-3 |
|---|---|
| SMILES | C1=C(C(=O)C2=C(N=CN=C2N1C3C(C(C(O3)CO)O)O)N)C(=O)N |
| InChIKey | SPBWHPXCWJLQRU-UHFFFAOYSA-N |
Product Overview
API-1(NSC 177223) (CAS 36707-00-3), with molecular formula C13H15N5O6 and molecular weight 337.10 g/mol. IUPAC: 4-amino-8-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-oxopyrido[2,3-d]pyrimidine-6-carboxamide.
Chemical Property Profile of API-1(NSC 177223)
Property Insights of API-1(NSC 177223)
The XLogP value of -1.9 indicates that API-1(NSC 177223) is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 185.0 Ų indicates high polarity, suggesting API-1(NSC 177223) may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, API-1(NSC 177223) has 5 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of API-1(NSC 177223)?
The CAS number of API-1(NSC 177223) is 36707-00-3.
What is the molecular formula of API-1(NSC 177223)?
The molecular formula of API-1(NSC 177223) is C13H15N5O6.
What is the molecular weight of API-1(NSC 177223)?
The molecular weight of API-1(NSC 177223) is 337.10 g/mol.
Where can I buy API-1(NSC 177223)?
You can request a quote for API-1(NSC 177223) directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for API-1(NSC 177223)?
Yes, KEHONG BIO provides custom synthesis services for API-1(NSC 177223) and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.