NCI 144-128
TL;DR: NCI 144-128 (CAS 36674-84-7) is a chemical compound with molecular formula C50H57N3O12 and molecular weight 891.39 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z,26E)-26-[(2,2-diphenylhydrazinyl)methylidene]-2,15,17,29-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23,27-trioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(28),2,4,9,19,21,25(29)-heptaen-13-yl] acetate
Also Known As: NCI 144-128, Rifamycin, 3-((diphenylhydrazono)methyl)-
| Molecular Formula | C50H57N3O12 |
|---|---|
| Molecular Weight | 891.39 g/mol |
| LogP | 7.01712 |
| Topological Polar Surface Area | 213.42 Ų |
| Hydrogen Bond Donors | 6 |
| Hydrogen Bond Acceptors | 14 |
| Rotatable Bonds | 6 |
| Exact Mass | 891.3942 |
| Heavy Atoms | 65 |
| Complexity | 2438.9534 |
Chemical Identifiers
| CAS Number | 36674-84-7 |
|---|---|
| SMILES | C[C@H]1/C=C/C=C(\C(=O)NC\2=C(C3=C(C4=C(C(=C3O)C)O[C@@](C4=O)(O/C=C/[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)OC(=O)C)C)OC)C)C(=O)/C2=C/NN(C5=CC=CC=C5)C6=CC=CC=C6)O)/C |
Product Overview
NCI 144-128 (CAS 36674-84-7), with molecular formula C50H57N3O12 and molecular weight 891.39 g/mol. IUPAC: [(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z,26E)-26-[(2,2-diphenylhydrazinyl)methylidene]-2,15,17,29-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23,27-trioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(28),2,4,9,19,21,25(29)-heptaen-13-yl] acetate.
Chemical Property Profile of NCI 144-128
Property Insights of NCI 144-128
The XLogP value of 7.01712 indicates that NCI 144-128 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 213.42 Ų indicates high polarity, suggesting NCI 144-128 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, NCI 144-128 has 6 hydrogen bond donor(s) and 14 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of NCI 144-128?
The CAS number of NCI 144-128 is 36674-84-7.
What is the molecular formula of NCI 144-128?
The molecular formula of NCI 144-128 is C50H57N3O12.
What is the molecular weight of NCI 144-128?
The molecular weight of NCI 144-128 is 891.39 g/mol.
Where can I buy NCI 144-128?
You can request a quote for NCI 144-128 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for NCI 144-128?
Yes, KEHONG BIO provides custom synthesis services for NCI 144-128 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.