(S)-Verapamil
TL;DR: (S)-Verapamil (CAS 36622-29-4) is a chemical compound with molecular formula C27H38N2O4 and molecular weight 454.28 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile
Also Known As: (-)-verapamil, Dexverapamil, (S)-VERAPAMIL, s-verapamil, verapamil-s
| Molecular Formula | C27H38N2O4 |
|---|---|
| Molecular Weight | 454.28 g/mol |
| LogP | 3.8 |
| Topological Polar Surface Area | 64.0 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 13 |
| Exact Mass | 454.28317 |
| Heavy Atoms | 33 |
| Complexity | 606.0 |
Chemical Identifiers
| CAS Number | 36622-29-4 |
|---|---|
| SMILES | CC(C)[C@](CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC |
| InChIKey | SGTNSNPWRIOYBX-MHZLTWQESA-N |
Product Overview
(S)-Verapamil (CAS 36622-29-4), with molecular formula C27H38N2O4 and molecular weight 454.28 g/mol. IUPAC: (2S)-2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile.
Chemical Property Profile of (S)-Verapamil
Property Insights of (S)-Verapamil
The XLogP value of 3.8 indicates that (S)-Verapamil is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 64.0 Ų falls within the moderate polarity range, balancing permeability and solubility for (S)-Verapamil. Following Lipinski's Rule of Five, (S)-Verapamil has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (S)-Verapamil?
The CAS number of (S)-Verapamil is 36622-29-4.
What is the molecular formula of (S)-Verapamil?
The molecular formula of (S)-Verapamil is C27H38N2O4.
What is the molecular weight of (S)-Verapamil?
The molecular weight of (S)-Verapamil is 454.28 g/mol.
Where can I buy (S)-Verapamil?
You can request a quote for (S)-Verapamil directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (S)-Verapamil?
Yes, KEHONG BIO provides custom synthesis services for (S)-Verapamil and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.