AY 9944 structure

AY 9944

TL;DR: AY 9944 (CAS 366-93-8) is a chemical compound with molecular formula C22H30Cl4N2 and molecular weight 462.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-[(2-chlorophenyl)methyl]-1-[4-[[(2-chlorophenyl)methylamino]methyl]cyclohexyl]methanamine;dihydrochloride

Also Known As: AY 9944 dihydrochloride, Shh Signaling Antagonist IV, AY9944dihydrochloride, trans-1,1'-(Cyclohexane-1,4-diyl)bis(N-(2-chlorobenzyl)methanamine) dihydrochloride, trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane dihydrochloride

CAS: 366-93-8
Molecular Formula C22H30Cl4N2
Molecular Weight 462.12 g/mol
LogP 6.52
Topological Polar Surface Area 24.1 Ų
Hydrogen Bond Donors 4
Hydrogen Bond Acceptors 2
Rotatable Bonds 8
Exact Mass 464.11337
Heavy Atoms 28
Complexity 348.0

Chemical Identifiers

CAS Number 366-93-8
SMILES C1CC(CCC1CNCC2=CC=CC=C2Cl)CNCC3=CC=CC=C3Cl.Cl.Cl
InChIKey NRVIEWRSGDDWHP-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.

Pharmaceutical Intermediates (1 patents)

Product Overview

AY 9944 (CAS 366-93-8), with molecular formula C22H30Cl4N2 and molecular weight 462.12 g/mol. IUPAC: N-[(2-chlorophenyl)methyl]-1-[4-[[(2-chlorophenyl)methylamino]methyl]cyclohexyl]methanamine;dihydrochloride.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of AY 9944

XLogP
6.52
TPSA (Topological Polar Surface Area)
24.1
Hydrogen Bond Donors
4
Hydrogen Bond Acceptors
2
Rotatable Bonds
8
Heavy Atoms
28
Complexity
348.0
Exact Mass
464.11337
Monoisotopic Mass
462.1163
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of AY 9944

The XLogP value of 6.52 indicates that AY 9944 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 24.1 Ų, AY 9944 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, AY 9944 has 4 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of AY 9944?

The CAS number of AY 9944 is 366-93-8.

What is the molecular formula of AY 9944?

The molecular formula of AY 9944 is C22H30Cl4N2.

What is the molecular weight of AY 9944?

The molecular weight of AY 9944 is 462.12 g/mol.

Where can I buy AY 9944?

You can request a quote for AY 9944 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for AY 9944?

Yes, KEHONG BIO provides custom synthesis services for AY 9944 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

🤖 科弘生物 AI 助手 ×
您好!我是 科弘生物 AI 助手。可以问我产品搜索、询价、样品或技术问题。如何帮助您?