Darexaban
TL;DR: Darexaban (CAS 365462-23-3) is a chemical compound with molecular formula C27H30N4O4 and molecular weight 474.23 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[2-hydroxy-6-[(4-methoxybenzoyl)amino]phenyl]-4-(4-methyl-1,4-diazepan-1-yl)benzamide
Also Known As: Darexaban, Tanexaban, darexabanum, Darexaban [INN], Tanexaban [INN]
| Molecular Formula | C27H30N4O4 |
|---|---|
| Molecular Weight | 474.23 g/mol |
| LogP | 4.0473 |
| Topological Polar Surface Area | 94.14 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 474.2267 |
| Heavy Atoms | 35 |
| Complexity | 1178.7905 |
Chemical Identifiers
| CAS Number | 365462-23-3 |
|---|---|
| SMILES | CN1CCCN(CC1)C2=CC=C(C=C2)C(=O)NC3=C(C=CC=C3O)NC(=O)C4=CC=C(C=C4)OC |
Product Overview
Darexaban (CAS 365462-23-3), with molecular formula C27H30N4O4 and molecular weight 474.23 g/mol. IUPAC: N-[2-hydroxy-6-[(4-methoxybenzoyl)amino]phenyl]-4-(4-methyl-1,4-diazepan-1-yl)benzamide.
Chemical Property Profile of Darexaban
Property Insights of Darexaban
The XLogP value of 4.0473 indicates that Darexaban is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 94.14 Ų falls within the moderate polarity range, balancing permeability and solubility for Darexaban. Following Lipinski's Rule of Five, Darexaban has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Darexaban?
The CAS number of Darexaban is 365462-23-3.
What is the molecular formula of Darexaban?
The molecular formula of Darexaban is C27H30N4O4.
What is the molecular weight of Darexaban?
The molecular weight of Darexaban is 474.23 g/mol.
Where can I buy Darexaban?
You can request a quote for Darexaban directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Darexaban?
Yes, KEHONG BIO provides custom synthesis services for Darexaban and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.