![[4-(3-Chlorophenyl)-5-(2-fluoro-4-pyridyl)-1,3-thiazol-2-yl]amine structure](/static/products/365/365428-46-2.png)
[4-(3-Chlorophenyl)-5-(2-fluoro-4-pyridyl)-1,3-thiazol-2-yl]amine
TL;DR: [4-(3-Chlorophenyl)-5-(2-fluoro-4-pyridyl)-1,3-thiazol-2-yl]amine (CAS 365428-46-2) is a chemical compound with molecular formula C14H9ClFN3S and molecular weight 305.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(3-chlorophenyl)-5-(2-fluoro-4-pyridinyl)-1,3-thiazol-2-amine
Also Known As: [4-(3-chlorophenyl)-5-(2-fluoro-4-pyridyl)-1,3-thiazol-2-yl]amine|4-(3-chlorophenyl)-5-(2-fluoropyridin-4-yl)-1,3-thiazol-2-amine
| Molecular Formula | C14H9ClFN3S |
|---|---|
| Molecular Weight | 305.02 g/mol |
| LogP | 4.2468 |
| Topological Polar Surface Area | 51.8 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 305.01898 |
| Heavy Atoms | 20 |
| Complexity | 709.61554 |
Chemical Identifiers
| CAS Number | 365428-46-2 |
|---|---|
| SMILES | C1=CC(=CC(=C1)Cl)C2=C(SC(=N2)N)C3=CC(=NC=C3)F |
Product Overview
[4-(3-Chlorophenyl)-5-(2-fluoro-4-pyridyl)-1,3-thiazol-2-yl]amine (CAS 365428-46-2), with molecular formula C14H9ClFN3S and molecular weight 305.02 g/mol. IUPAC: 4-(3-chlorophenyl)-5-(2-fluoro-4-pyridinyl)-1,3-thiazol-2-amine.
Chemical Property Profile of [4-(3-Chlorophenyl)-5-(2-fluoro-4-pyridyl)-1,3-thiazol-2-yl]amine
Property Insights of [4-(3-Chlorophenyl)-5-(2-fluoro-4-pyridyl)-1,3-thiazol-2-yl]amine
The XLogP value of 4.2468 indicates that [4-(3-Chlorophenyl)-5-(2-fluoro-4-pyridyl)-1,3-thiazol-2-yl]amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.8 Ų, [4-(3-Chlorophenyl)-5-(2-fluoro-4-pyridyl)-1,3-thiazol-2-yl]amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, [4-(3-Chlorophenyl)-5-(2-fluoro-4-pyridyl)-1,3-thiazol-2-yl]amine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of [4-(3-Chlorophenyl)-5-(2-fluoro-4-pyridyl)-1,3-thiazol-2-yl]amine?
The CAS number of [4-(3-Chlorophenyl)-5-(2-fluoro-4-pyridyl)-1,3-thiazol-2-yl]amine is 365428-46-2.
What is the molecular formula of [4-(3-Chlorophenyl)-5-(2-fluoro-4-pyridyl)-1,3-thiazol-2-yl]amine?
The molecular formula of [4-(3-Chlorophenyl)-5-(2-fluoro-4-pyridyl)-1,3-thiazol-2-yl]amine is C14H9ClFN3S.
What is the molecular weight of [4-(3-Chlorophenyl)-5-(2-fluoro-4-pyridyl)-1,3-thiazol-2-yl]amine?
The molecular weight of [4-(3-Chlorophenyl)-5-(2-fluoro-4-pyridyl)-1,3-thiazol-2-yl]amine is 305.02 g/mol.
Where can I buy [4-(3-Chlorophenyl)-5-(2-fluoro-4-pyridyl)-1,3-thiazol-2-yl]amine?
You can request a quote for [4-(3-Chlorophenyl)-5-(2-fluoro-4-pyridyl)-1,3-thiazol-2-yl]amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for [4-(3-Chlorophenyl)-5-(2-fluoro-4-pyridyl)-1,3-thiazol-2-yl]amine?
Yes, KEHONG BIO provides custom synthesis services for [4-(3-Chlorophenyl)-5-(2-fluoro-4-pyridyl)-1,3-thiazol-2-yl]amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.