CDK2-IN-18
TL;DR: CDK2-IN-18 (CAS 364735-73-9) is a chemical compound with molecular formula C21H23N7O2S and molecular weight 437.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[3-(2,4-dimethyl-1,3-thiazol-5-yl)-4-oxo-2H-indeno[1,2-c]pyrazol-5-yl]-3-(4-methylpiperazin-1-yl)urea
Also Known As: CDK2-IN-18, C3 heterocyle indenopyrazole 8q, 2b52, 1-(3-(2,4-DIMETHYLTHIAZOL-5-YL)-4-OXO-2,4-DIHYDROINDENO[1,2-C]PYRAZOL-5-YL)-3-(4-METHYLPIPERAZIN-1-YL)UREA, J2.042.676D
| Molecular Formula | C21H23N7O2S |
|---|---|
| Molecular Weight | 437.16 g/mol |
| LogP | 2.64534 |
| Topological Polar Surface Area | 106.25 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 3 |
| Exact Mass | 437.1634 |
| Heavy Atoms | 31 |
| Complexity | 1190.5524 |
Chemical Identifiers
| CAS Number | 364735-73-9 |
|---|---|
| SMILES | CC1=C(SC(=N1)C)C2=C3C(=NN2)C4=C(C3=O)C(=CC=C4)NC(=O)NN5CCN(CC5)C |
Product Overview
CDK2-IN-18 (CAS 364735-73-9), with molecular formula C21H23N7O2S and molecular weight 437.16 g/mol. IUPAC: 1-[3-(2,4-dimethyl-1,3-thiazol-5-yl)-4-oxo-2H-indeno[1,2-c]pyrazol-5-yl]-3-(4-methylpiperazin-1-yl)urea.
Chemical Property Profile of CDK2-IN-18
Property Insights of CDK2-IN-18
The XLogP value of 2.64534 suggests moderate lipophilicity, balancing water solubility and membrane permeability for CDK2-IN-18. The TPSA of 106.25 Ų falls within the moderate polarity range, balancing permeability and solubility for CDK2-IN-18. Following Lipinski's Rule of Five, CDK2-IN-18 has 3 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of CDK2-IN-18?
The CAS number of CDK2-IN-18 is 364735-73-9.
What is the molecular formula of CDK2-IN-18?
The molecular formula of CDK2-IN-18 is C21H23N7O2S.
What is the molecular weight of CDK2-IN-18?
The molecular weight of CDK2-IN-18 is 437.16 g/mol.
Where can I buy CDK2-IN-18?
You can request a quote for CDK2-IN-18 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for CDK2-IN-18?
Yes, KEHONG BIO provides custom synthesis services for CDK2-IN-18 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.