Niclosamide piperazine
TL;DR: Niclosamide piperazine (CAS 36466-48-5) is a chemical compound with molecular formula C17H18Cl2N4O4 and molecular weight 412.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide;piperazine
Also Known As: Niclosamide piperazine, Taenifugin, Fenasal piperazine, Phenasal piperazine, Niclosamid-piperazin
| Molecular Formula | C17H18Cl2N4O4 |
|---|---|
| Molecular Weight | 412.07 g/mol |
| LogP | 3.0387 |
| Topological Polar Surface Area | 116.53 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 412.0705 |
| Heavy Atoms | 27 |
| Complexity | 817.0661 |
Chemical Identifiers
| CAS Number | 36466-48-5 |
|---|---|
| SMILES | C1CNCCN1.C1=CC(=C(C=C1[N+](=O)[O-])Cl)NC(=O)C2=C(C=CC(=C2)Cl)O |
Product Overview
Niclosamide piperazine (CAS 36466-48-5), with molecular formula C17H18Cl2N4O4 and molecular weight 412.07 g/mol. IUPAC: 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide;piperazine.
Chemical Property Profile of Niclosamide piperazine
Property Insights of Niclosamide piperazine
The XLogP value of 3.0387 indicates that Niclosamide piperazine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 116.53 Ų falls within the moderate polarity range, balancing permeability and solubility for Niclosamide piperazine. Following Lipinski's Rule of Five, Niclosamide piperazine has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Niclosamide piperazine?
The CAS number of Niclosamide piperazine is 36466-48-5.
What is the molecular formula of Niclosamide piperazine?
The molecular formula of Niclosamide piperazine is C17H18Cl2N4O4.
What is the molecular weight of Niclosamide piperazine?
The molecular weight of Niclosamide piperazine is 412.07 g/mol.
Where can I buy Niclosamide piperazine?
You can request a quote for Niclosamide piperazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Niclosamide piperazine?
Yes, KEHONG BIO provides custom synthesis services for Niclosamide piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.