(E)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-4-(((1-methyl-1H-imidazol-2-yl)thio)methyl)benzohydrazide
TL;DR: (E)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-4-(((1-methyl-1H-imidazol-2-yl)thio)methyl)benzohydrazide (CAS 364384-53-2) is a chemical compound with molecular formula C18H17ClN4OS2 and molecular weight 404.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(E)-1-(5-chlorothiophen-2-yl)ethylideneamino]-4-[(1-methylimidazol-2-yl)sulfanylmethyl]benzamide
Also Known As: (E)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-4-(((1-methyl-1H-imidazol-2-yl)thio)methyl)benzohydrazide, N'-[(1E)-1-(5-chlorothiophen-2-yl)ethylidene]-4-{[(1-methyl-1H-imidazol-2-yl)sulfanyl]methyl}benzohydrazide, N-[(E)-1-(5-chlorothiophen-2-yl)ethylideneamino]-4-[(1-methylimidazol-2-yl)sulfanylmethyl]benzamide
| Molecular Formula | C18H17ClN4OS2 |
|---|---|
| Molecular Weight | 404.05 g/mol |
| LogP | 4.5813 |
| Topological Polar Surface Area | 59.28 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 404.05322 |
| Heavy Atoms | 26 |
| Complexity | 930.8315 |
Chemical Identifiers
| CAS Number | 364384-53-2 |
|---|---|
| SMILES | C/C(=N\NC(=O)C1=CC=C(C=C1)CSC2=NC=CN2C)/C3=CC=C(S3)Cl |
Product Overview
(E)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-4-(((1-methyl-1H-imidazol-2-yl)thio)methyl)benzohydrazide (CAS 364384-53-2), with molecular formula C18H17ClN4OS2 and molecular weight 404.05 g/mol. IUPAC: N-[(E)-1-(5-chlorothiophen-2-yl)ethylideneamino]-4-[(1-methylimidazol-2-yl)sulfanylmethyl]benzamide.
Chemical Property Profile of (E)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-4-(((1-methyl-1H-imidazol-2-yl)thio)methyl)benzohydrazide
Property Insights of (E)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-4-(((1-methyl-1H-imidazol-2-yl)thio)methyl)benzohydrazide
The XLogP value of 4.5813 indicates that (E)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-4-(((1-methyl-1H-imidazol-2-yl)thio)methyl)benzohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.28 Ų, (E)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-4-(((1-methyl-1H-imidazol-2-yl)thio)methyl)benzohydrazide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-4-(((1-methyl-1H-imidazol-2-yl)thio)methyl)benzohydrazide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-4-(((1-methyl-1H-imidazol-2-yl)thio)methyl)benzohydrazide?
The CAS number of (E)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-4-(((1-methyl-1H-imidazol-2-yl)thio)methyl)benzohydrazide is 364384-53-2.
What is the molecular formula of (E)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-4-(((1-methyl-1H-imidazol-2-yl)thio)methyl)benzohydrazide?
The molecular formula of (E)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-4-(((1-methyl-1H-imidazol-2-yl)thio)methyl)benzohydrazide is C18H17ClN4OS2.
What is the molecular weight of (E)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-4-(((1-methyl-1H-imidazol-2-yl)thio)methyl)benzohydrazide?
The molecular weight of (E)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-4-(((1-methyl-1H-imidazol-2-yl)thio)methyl)benzohydrazide is 404.05 g/mol.
Where can I buy (E)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-4-(((1-methyl-1H-imidazol-2-yl)thio)methyl)benzohydrazide?
You can request a quote for (E)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-4-(((1-methyl-1H-imidazol-2-yl)thio)methyl)benzohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-4-(((1-methyl-1H-imidazol-2-yl)thio)methyl)benzohydrazide?
Yes, KEHONG BIO provides custom synthesis services for (E)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-4-(((1-methyl-1H-imidazol-2-yl)thio)methyl)benzohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.