(1S,3s,E)-N'-(2,4-difluorobenzylidene)adamantane-1-carbohydrazide structure

(1S,3s,E)-N'-(2,4-difluorobenzylidene)adamantane-1-carbohydrazide

TL;DR: (1S,3s,E)-N'-(2,4-difluorobenzylidene)adamantane-1-carbohydrazide (CAS 363604-79-9) is a chemical compound with molecular formula C18H20F2N2O and molecular weight 318.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-[(E)-(2,4-difluorophenyl)methylideneamino]adamantane-1-carboxamide

Also Known As: (1S,3s,E)-N'-(2,4-difluorobenzylidene)adamantane-1-carbohydrazide, N-[(E)-(2,4-difluorophenyl)methylideneamino]adamantane-1-carboxamide, F0346-0925, N'-[(1E)-(2,4-DIFLUOROPHENYL)METHYLIDENE]ADAMANTANE-1-CARBOHYDRAZIDE, N'-[(E)-(2,4-DIFLUOROPHENYL)METHYLIDENE]ADAMANTANE-1-CARBOHYDRAZIDE

CAS: 363604-79-9
Molecular Formula C18H20F2N2O
Molecular Weight 318.15 g/mol
LogP 3.6313
Topological Polar Surface Area 41.46 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 2
Rotatable Bonds 3
Exact Mass 318.15436
Heavy Atoms 23
Complexity 635.70123

Chemical Identifiers

CAS Number 363604-79-9
SMILES C1C2CC3CC1CC(C2)(C3)C(=O)N/N=C/C4=C(C=C(C=C4)F)F

Product Overview

(1S,3s,E)-N'-(2,4-difluorobenzylidene)adamantane-1-carbohydrazide (CAS 363604-79-9), with molecular formula C18H20F2N2O and molecular weight 318.15 g/mol. IUPAC: N-[(E)-(2,4-difluorophenyl)methylideneamino]adamantane-1-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of (1S,3s,E)-N'-(2,4-difluorobenzylidene)adamantane-1-carbohydrazide

XLogP
3.6313
TPSA (Topological Polar Surface Area)
41.46
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
2
Rotatable Bonds
3
Heavy Atoms
23
Complexity
635.70123
Exact Mass
318.15436
Monoisotopic Mass
318.15436
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of (1S,3s,E)-N'-(2,4-difluorobenzylidene)adamantane-1-carbohydrazide

The XLogP value of 3.6313 indicates that (1S,3s,E)-N'-(2,4-difluorobenzylidene)adamantane-1-carbohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.46 Ų, (1S,3s,E)-N'-(2,4-difluorobenzylidene)adamantane-1-carbohydrazide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (1S,3s,E)-N'-(2,4-difluorobenzylidene)adamantane-1-carbohydrazide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of (1S,3s,E)-N'-(2,4-difluorobenzylidene)adamantane-1-carbohydrazide?

The CAS number of (1S,3s,E)-N'-(2,4-difluorobenzylidene)adamantane-1-carbohydrazide is 363604-79-9.

What is the molecular formula of (1S,3s,E)-N'-(2,4-difluorobenzylidene)adamantane-1-carbohydrazide?

The molecular formula of (1S,3s,E)-N'-(2,4-difluorobenzylidene)adamantane-1-carbohydrazide is C18H20F2N2O.

What is the molecular weight of (1S,3s,E)-N'-(2,4-difluorobenzylidene)adamantane-1-carbohydrazide?

The molecular weight of (1S,3s,E)-N'-(2,4-difluorobenzylidene)adamantane-1-carbohydrazide is 318.15 g/mol.

Where can I buy (1S,3s,E)-N'-(2,4-difluorobenzylidene)adamantane-1-carbohydrazide?

You can request a quote for (1S,3s,E)-N'-(2,4-difluorobenzylidene)adamantane-1-carbohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for (1S,3s,E)-N'-(2,4-difluorobenzylidene)adamantane-1-carbohydrazide?

Yes, KEHONG BIO provides custom synthesis services for (1S,3s,E)-N'-(2,4-difluorobenzylidene)adamantane-1-carbohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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