5-tert-butyl-6-chloro-N-(2-methylphenyl)pyrazine-2-carboxamide
TL;DR: 5-tert-butyl-6-chloro-N-(2-methylphenyl)pyrazine-2-carboxamide (CAS 362622-86-4) is a chemical compound with molecular formula C16H18ClN3O and molecular weight 303.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-tert-butyl-6-chloro-N-(2-methylphenyl)pyrazine-2-carboxamide
Also Known As: Pyrazinecarboxamide,6-chloro-N-(2-methylphenyl), 5-(tert-butyl)-6-chloro-N-(o-tolyl)pyrazine-2-carboxamide, 5-tert-butyl-6-chloro-N-(2-methylphenyl)pyrazine-2-carboxamide
| Molecular Formula | C16H18ClN3O |
|---|---|
| Molecular Weight | 303.11 g/mol |
| LogP | 3.98822 |
| Topological Polar Surface Area | 54.88 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 303.11383 |
| Heavy Atoms | 21 |
| Complexity | 677.4626 |
Chemical Identifiers
| CAS Number | 362622-86-4 |
|---|---|
| SMILES | CC1=CC=CC=C1NC(=O)C2=CN=C(C(=N2)Cl)C(C)(C)C |
Product Overview
5-tert-butyl-6-chloro-N-(2-methylphenyl)pyrazine-2-carboxamide (CAS 362622-86-4), with molecular formula C16H18ClN3O and molecular weight 303.11 g/mol. IUPAC: 5-tert-butyl-6-chloro-N-(2-methylphenyl)pyrazine-2-carboxamide.
Chemical Property Profile of 5-tert-butyl-6-chloro-N-(2-methylphenyl)pyrazine-2-carboxamide
Property Insights of 5-tert-butyl-6-chloro-N-(2-methylphenyl)pyrazine-2-carboxamide
The XLogP value of 3.98822 indicates that 5-tert-butyl-6-chloro-N-(2-methylphenyl)pyrazine-2-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 54.88 Ų, 5-tert-butyl-6-chloro-N-(2-methylphenyl)pyrazine-2-carboxamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-tert-butyl-6-chloro-N-(2-methylphenyl)pyrazine-2-carboxamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-tert-butyl-6-chloro-N-(2-methylphenyl)pyrazine-2-carboxamide?
The CAS number of 5-tert-butyl-6-chloro-N-(2-methylphenyl)pyrazine-2-carboxamide is 362622-86-4.
What is the molecular formula of 5-tert-butyl-6-chloro-N-(2-methylphenyl)pyrazine-2-carboxamide?
The molecular formula of 5-tert-butyl-6-chloro-N-(2-methylphenyl)pyrazine-2-carboxamide is C16H18ClN3O.
What is the molecular weight of 5-tert-butyl-6-chloro-N-(2-methylphenyl)pyrazine-2-carboxamide?
The molecular weight of 5-tert-butyl-6-chloro-N-(2-methylphenyl)pyrazine-2-carboxamide is 303.11 g/mol.
Where can I buy 5-tert-butyl-6-chloro-N-(2-methylphenyl)pyrazine-2-carboxamide?
You can request a quote for 5-tert-butyl-6-chloro-N-(2-methylphenyl)pyrazine-2-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-tert-butyl-6-chloro-N-(2-methylphenyl)pyrazine-2-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for 5-tert-butyl-6-chloro-N-(2-methylphenyl)pyrazine-2-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.