Meclizine Monohydrochloride
TL;DR: Meclizine Monohydrochloride (CAS 36236-67-6) is a chemical compound with molecular formula C25H28Cl2N2 and molecular weight 426.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(4-chlorophenyl)-phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine;hydrochloride
Also Known As: Duremesin, meclizine diHCl, Meclizine Monohydrochloride, Meclozine hydrochloride, Meclizine Hcl
| Molecular Formula | C25H28Cl2N2 |
|---|---|
| Molecular Weight | 426.16 g/mol |
| LogP | 5.98 |
| Topological Polar Surface Area | 6.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 5 |
| Exact Mass | 426.16296 |
| Heavy Atoms | 29 |
| Complexity | 447.0 |
Chemical Identifiers
| CAS Number | 36236-67-6 |
|---|---|
| SMILES | CC1=CC(=CC=C1)CN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=C(C=C4)Cl.Cl |
| InChIKey | GJNMJOHYRWHJQB-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 13 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Meclizine Monohydrochloride (CAS 36236-67-6), with molecular formula C25H28Cl2N2 and molecular weight 426.16 g/mol. IUPAC: 1-[(4-chlorophenyl)-phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine;hydrochloride.
Chemical Property Profile of Meclizine Monohydrochloride
Property Insights of Meclizine Monohydrochloride
The XLogP value of 5.98 indicates that Meclizine Monohydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 6.5 Ų, Meclizine Monohydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Meclizine Monohydrochloride has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Meclizine Monohydrochloride?
The CAS number of Meclizine Monohydrochloride is 36236-67-6.
What is the molecular formula of Meclizine Monohydrochloride?
The molecular formula of Meclizine Monohydrochloride is C25H28Cl2N2.
What is the molecular weight of Meclizine Monohydrochloride?
The molecular weight of Meclizine Monohydrochloride is 426.16 g/mol.
Where can I buy Meclizine Monohydrochloride?
You can request a quote for Meclizine Monohydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Meclizine Monohydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Meclizine Monohydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.