Guafecainol
TL;DR: Guafecainol (CAS 36199-78-7) is a chemical compound with molecular formula C16H27NO4 and molecular weight 297.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[2-(diethylamino)ethoxy]-3-(2-methoxyphenoxy)propan-2-ol
Also Known As: Guafecainol, Guafecainolum, Brufacain, Brufacaine, Guafecainol [INN]
| Molecular Formula | C16H27NO4 |
|---|---|
| Molecular Weight | 297.19 g/mol |
| LogP | 2.7 |
| Topological Polar Surface Area | 51.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 11 |
| Exact Mass | 297.194 |
| Heavy Atoms | 21 |
| Complexity | 248.0 |
Chemical Identifiers
| CAS Number | 36199-78-7 |
|---|---|
| SMILES | CCN(CC)CCOCC(COC1=CC=CC=C1OC)O |
| InChIKey | DHCZIHSQOICDAY-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Guafecainol (CAS 36199-78-7), with molecular formula C16H27NO4 and molecular weight 297.19 g/mol. IUPAC: 1-[2-(diethylamino)ethoxy]-3-(2-methoxyphenoxy)propan-2-ol.
Chemical Property Profile of Guafecainol
Property Insights of Guafecainol
The XLogP value of 2.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Guafecainol. With a topological polar surface area (TPSA) of 51.2 Ų, Guafecainol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Guafecainol has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Guafecainol?
The CAS number of Guafecainol is 36199-78-7.
What is the molecular formula of Guafecainol?
The molecular formula of Guafecainol is C16H27NO4.
What is the molecular weight of Guafecainol?
The molecular weight of Guafecainol is 297.19 g/mol.
Where can I buy Guafecainol?
You can request a quote for Guafecainol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Guafecainol?
Yes, KEHONG BIO provides custom synthesis services for Guafecainol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.