(+-)-Halofantrine hydrochloride
TL;DR: (+-)-Halofantrine hydrochloride (CAS 36167-63-2) is a chemical compound with molecular formula C26H31Cl3F3NO and molecular weight 535.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-(dibutylamino)-1-[1,3-dichloro-6-(trifluoromethyl)phenanthren-9-yl]propan-1-ol;hydrochloride
Also Known As: HALOFANTRINE HYDROCHLORIDE, Halfan, Halofantrine, Halofantrine HCl, Halofantrino
| Molecular Formula | C26H31Cl3F3NO |
|---|---|
| Molecular Weight | 535.14 g/mol |
| LogP | 9.07 |
| Topological Polar Surface Area | 23.5 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 10 |
| Exact Mass | 535.14233 |
| Heavy Atoms | 34 |
| Complexity | 584.0 |
Chemical Identifiers
| CAS Number | 36167-63-2 |
|---|---|
| SMILES | CCCCN(CCCC)CCC(C1=C2C=CC(=CC2=C3C=C(C=C(C3=C1)Cl)Cl)C(F)(F)F)O.Cl |
| InChIKey | WANGFTDWOFGECH-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 9 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
(+-)-Halofantrine hydrochloride (CAS 36167-63-2), with molecular formula C26H31Cl3F3NO and molecular weight 535.14 g/mol. IUPAC: 3-(dibutylamino)-1-[1,3-dichloro-6-(trifluoromethyl)phenanthren-9-yl]propan-1-ol;hydrochloride.
Chemical Property Profile of (+-)-Halofantrine hydrochloride
Property Insights of (+-)-Halofantrine hydrochloride
The XLogP value of 9.07 indicates that (+-)-Halofantrine hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 23.5 Ų, (+-)-Halofantrine hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (+-)-Halofantrine hydrochloride has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (+-)-Halofantrine hydrochloride?
The CAS number of (+-)-Halofantrine hydrochloride is 36167-63-2.
What is the molecular formula of (+-)-Halofantrine hydrochloride?
The molecular formula of (+-)-Halofantrine hydrochloride is C26H31Cl3F3NO.
What is the molecular weight of (+-)-Halofantrine hydrochloride?
The molecular weight of (+-)-Halofantrine hydrochloride is 535.14 g/mol.
Where can I buy (+-)-Halofantrine hydrochloride?
You can request a quote for (+-)-Halofantrine hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (+-)-Halofantrine hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for (+-)-Halofantrine hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.