5-trans-PGE2
TL;DR: 5-trans-PGE2 (CAS 36150-00-2) is a chemical compound with molecular formula C20H32O5 and molecular weight 352.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid
Also Known As: trans-Dinoprostone, 5-trans Prostaglandin E2, 5-trans-Prostaglandin E2, 5-trans-PGE2, Lipoalprostadil
| Molecular Formula | C20H32O5 |
|---|---|
| Molecular Weight | 352.22 g/mol |
| LogP | 3.2511 |
| Topological Polar Surface Area | 94.83 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 12 |
| Exact Mass | 352.22498 |
| Heavy Atoms | 25 |
| Complexity | 468.70697 |
Chemical Identifiers
| CAS Number | 36150-00-2 |
|---|---|
| SMILES | CCCCC[C@@H](/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1C/C=C/CCCC(=O)O)O)O |
Product Overview
5-trans-PGE2 (CAS 36150-00-2), with molecular formula C20H32O5 and molecular weight 352.22 g/mol. IUPAC: (E)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid.
Chemical Property Profile of 5-trans-PGE2
Property Insights of 5-trans-PGE2
The XLogP value of 3.2511 indicates that 5-trans-PGE2 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 94.83 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-trans-PGE2. Following Lipinski's Rule of Five, 5-trans-PGE2 has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-trans-PGE2?
The CAS number of 5-trans-PGE2 is 36150-00-2.
What is the molecular formula of 5-trans-PGE2?
The molecular formula of 5-trans-PGE2 is C20H32O5.
What is the molecular weight of 5-trans-PGE2?
The molecular weight of 5-trans-PGE2 is 352.22 g/mol.
Where can I buy 5-trans-PGE2?
You can request a quote for 5-trans-PGE2 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-trans-PGE2?
Yes, KEHONG BIO provides custom synthesis services for 5-trans-PGE2 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.