N-(4-(4-nitrothiophen-2-yl)thiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzamide
TL;DR: N-(4-(4-nitrothiophen-2-yl)thiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzamide (CAS 361480-40-2) is a chemical compound with molecular formula C19H18N4O5S3 and molecular weight 478.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[4-(4-nitrothiophen-2-yl)-1,3-thiazol-2-yl]-4-piperidin-1-ylsulfonylbenzamide
Also Known As: F0466-0235, N-(4-(4-nitrothiophen-2-yl)thiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzamide, N-[4-(4-nitrothiophen-2-yl)-1,3-thiazol-2-yl]-4-(piperidine-1-sulfonyl)benzamide, N-[4-(4-nitrothiophen-2-yl)-1,3-thiazol-2-yl]-4-piperidin-1-ylsulfonylbenzamide, N-[4-(4-nitrothiophen-2-yl)-1,3-thiazol-2-yl]-4-(1-piperidylsulfonyl)benzamide
| Molecular Formula | C19H18N4O5S3 |
|---|---|
| Molecular Weight | 478.04 g/mol |
| LogP | 4.2067 |
| Topological Polar Surface Area | 122.51 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 6 |
| Exact Mass | 478.04395 |
| Heavy Atoms | 31 |
| Complexity | 1211.4114 |
Chemical Identifiers
| CAS Number | 361480-40-2 |
|---|---|
| SMILES | C1CCN(CC1)S(=O)(=O)C2=CC=C(C=C2)C(=O)NC3=NC(=CS3)C4=CC(=CS4)[N+](=O)[O-] |
Product Overview
N-(4-(4-nitrothiophen-2-yl)thiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzamide (CAS 361480-40-2), with molecular formula C19H18N4O5S3 and molecular weight 478.04 g/mol. IUPAC: N-[4-(4-nitrothiophen-2-yl)-1,3-thiazol-2-yl]-4-piperidin-1-ylsulfonylbenzamide.
Chemical Property Profile of N-(4-(4-nitrothiophen-2-yl)thiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzamide
Property Insights of N-(4-(4-nitrothiophen-2-yl)thiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzamide
The XLogP value of 4.2067 indicates that N-(4-(4-nitrothiophen-2-yl)thiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 122.51 Ų falls within the moderate polarity range, balancing permeability and solubility for N-(4-(4-nitrothiophen-2-yl)thiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzamide. Following Lipinski's Rule of Five, N-(4-(4-nitrothiophen-2-yl)thiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzamide has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(4-(4-nitrothiophen-2-yl)thiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzamide?
The CAS number of N-(4-(4-nitrothiophen-2-yl)thiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzamide is 361480-40-2.
What is the molecular formula of N-(4-(4-nitrothiophen-2-yl)thiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzamide?
The molecular formula of N-(4-(4-nitrothiophen-2-yl)thiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzamide is C19H18N4O5S3.
What is the molecular weight of N-(4-(4-nitrothiophen-2-yl)thiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzamide?
The molecular weight of N-(4-(4-nitrothiophen-2-yl)thiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzamide is 478.04 g/mol.
Where can I buy N-(4-(4-nitrothiophen-2-yl)thiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzamide?
You can request a quote for N-(4-(4-nitrothiophen-2-yl)thiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(4-(4-nitrothiophen-2-yl)thiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzamide?
Yes, KEHONG BIO provides custom synthesis services for N-(4-(4-nitrothiophen-2-yl)thiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.