N-(1-acetyl-2,2,4-trimethyl-4-phenyl-3H-quinolin-6-yl)-2,2,2-trifluoroacetamide
TL;DR: N-(1-acetyl-2,2,4-trimethyl-4-phenyl-3H-quinolin-6-yl)-2,2,2-trifluoroacetamide (CAS 360760-14-1) is a chemical compound with molecular formula C22H23F3N2O2 and molecular weight 404.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(1-acetyl-2,2,4-trimethyl-4-phenyl-3H-quinolin-6-yl)-2,2,2-trifluoroacetamide
Also Known As: BIM-0015306.P001, N-(1-acetyl-2,2,4-trimethyl-4-phenyl-3H-quinolin-6-yl)-2,2,2-trifluoroacetamide, N-(1-acetyl-2,2,4-trimethyl-4-phenyl-1,2,3,4-tetrahydroquinolin-6-yl)-2,2,2-trifluoroacetamide, Acetamide, 2,2,2-trifluoro-N-(1,2,3,4-tetrahydro-1-acetyl-2,2,4-trimethyl-4-phenylquinolin-6-yl)-, N-(1-Acetyl-2,2,4-trimethyl-4-phenyl-1,2,3,4-tetrahydro-6-quinolinyl)-2,2,2-trifluoroacetamide #
| Molecular Formula | C22H23F3N2O2 |
|---|---|
| Molecular Weight | 404.17 g/mol |
| LogP | 4.6 |
| Topological Polar Surface Area | 49.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 404.17117 |
| Heavy Atoms | 29 |
| Complexity | 642.0 |
Chemical Identifiers
| CAS Number | 360760-14-1 |
|---|---|
| SMILES | CC(=O)N1C2=C(C=C(C=C2)NC(=O)C(F)(F)F)C(CC1(C)C)(C)C3=CC=CC=C3 |
| InChIKey | ARWKEHPZVPYGDT-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
N-(1-acetyl-2,2,4-trimethyl-4-phenyl-3H-quinolin-6-yl)-2,2,2-trifluoroacetamide (CAS 360760-14-1), with molecular formula C22H23F3N2O2 and molecular weight 404.17 g/mol. IUPAC: N-(1-acetyl-2,2,4-trimethyl-4-phenyl-3H-quinolin-6-yl)-2,2,2-trifluoroacetamide.
Chemical Property Profile of N-(1-acetyl-2,2,4-trimethyl-4-phenyl-3H-quinolin-6-yl)-2,2,2-trifluoroacetamide
Property Insights of N-(1-acetyl-2,2,4-trimethyl-4-phenyl-3H-quinolin-6-yl)-2,2,2-trifluoroacetamide
The XLogP value of 4.6 indicates that N-(1-acetyl-2,2,4-trimethyl-4-phenyl-3H-quinolin-6-yl)-2,2,2-trifluoroacetamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.4 Ų, N-(1-acetyl-2,2,4-trimethyl-4-phenyl-3H-quinolin-6-yl)-2,2,2-trifluoroacetamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(1-acetyl-2,2,4-trimethyl-4-phenyl-3H-quinolin-6-yl)-2,2,2-trifluoroacetamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(1-acetyl-2,2,4-trimethyl-4-phenyl-3H-quinolin-6-yl)-2,2,2-trifluoroacetamide?
The CAS number of N-(1-acetyl-2,2,4-trimethyl-4-phenyl-3H-quinolin-6-yl)-2,2,2-trifluoroacetamide is 360760-14-1.
What is the molecular formula of N-(1-acetyl-2,2,4-trimethyl-4-phenyl-3H-quinolin-6-yl)-2,2,2-trifluoroacetamide?
The molecular formula of N-(1-acetyl-2,2,4-trimethyl-4-phenyl-3H-quinolin-6-yl)-2,2,2-trifluoroacetamide is C22H23F3N2O2.
What is the molecular weight of N-(1-acetyl-2,2,4-trimethyl-4-phenyl-3H-quinolin-6-yl)-2,2,2-trifluoroacetamide?
The molecular weight of N-(1-acetyl-2,2,4-trimethyl-4-phenyl-3H-quinolin-6-yl)-2,2,2-trifluoroacetamide is 404.17 g/mol.
Where can I buy N-(1-acetyl-2,2,4-trimethyl-4-phenyl-3H-quinolin-6-yl)-2,2,2-trifluoroacetamide?
You can request a quote for N-(1-acetyl-2,2,4-trimethyl-4-phenyl-3H-quinolin-6-yl)-2,2,2-trifluoroacetamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(1-acetyl-2,2,4-trimethyl-4-phenyl-3H-quinolin-6-yl)-2,2,2-trifluoroacetamide?
Yes, KEHONG BIO provides custom synthesis services for N-(1-acetyl-2,2,4-trimethyl-4-phenyl-3H-quinolin-6-yl)-2,2,2-trifluoroacetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.