Thymidylyl(3'-5')-5'-thio-5'-deoxythymidine structure

Thymidylyl(3'-5')-5'-thio-5'-deoxythymidine

TL;DR: Thymidylyl(3'-5')-5'-thio-5'-deoxythymidine (CAS 35931-57-8) is a chemical compound with molecular formula C20H27N4O11PS and molecular weight 562.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-[[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methylsulfanyl]phosphinic acid

Also Known As: TPST, d(Tpst), Thymidyl-PS-thymidine, Thymidylyl(3'-5')-5'-thio-5'-deoxythymidine, Thymidine, thymidylyl-(3'-5')-5'-thio-

CAS: 35931-57-8
Molecular Formula C20H27N4O11PS
Molecular Weight 562.11 g/mol
LogP -1.14936
Topological Polar Surface Area 215.17 Ų
Hydrogen Bond Donors 5
Hydrogen Bond Acceptors 11
Rotatable Bonds 8
Exact Mass 562.11346
Heavy Atoms 37
Complexity 1331.34

Chemical Identifiers

CAS Number 35931-57-8
SMILES CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)COP(=O)(O)SC[C@@H]3[C@H](C[C@@H](O3)N4C=C(C(=O)NC4=O)C)O)O

Product Overview

Thymidylyl(3'-5')-5'-thio-5'-deoxythymidine (CAS 35931-57-8), with molecular formula C20H27N4O11PS and molecular weight 562.11 g/mol. IUPAC: [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-[[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methylsulfanyl]phosphinic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Thymidylyl(3'-5')-5'-thio-5'-deoxythymidine

XLogP
-1.14936
TPSA (Topological Polar Surface Area)
215.17
Hydrogen Bond Donors
5
Hydrogen Bond Acceptors
11
Rotatable Bonds
8
Heavy Atoms
37
Complexity
1331.34
Exact Mass
562.11346
Monoisotopic Mass
562.11346
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Thymidylyl(3'-5')-5'-thio-5'-deoxythymidine

The XLogP value of -1.14936 indicates that Thymidylyl(3'-5')-5'-thio-5'-deoxythymidine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 215.17 Ų indicates high polarity, suggesting Thymidylyl(3'-5')-5'-thio-5'-deoxythymidine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Thymidylyl(3'-5')-5'-thio-5'-deoxythymidine has 5 hydrogen bond donor(s) and 11 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Thymidylyl(3'-5')-5'-thio-5'-deoxythymidine?

The CAS number of Thymidylyl(3'-5')-5'-thio-5'-deoxythymidine is 35931-57-8.

What is the molecular formula of Thymidylyl(3'-5')-5'-thio-5'-deoxythymidine?

The molecular formula of Thymidylyl(3'-5')-5'-thio-5'-deoxythymidine is C20H27N4O11PS.

What is the molecular weight of Thymidylyl(3'-5')-5'-thio-5'-deoxythymidine?

The molecular weight of Thymidylyl(3'-5')-5'-thio-5'-deoxythymidine is 562.11 g/mol.

Where can I buy Thymidylyl(3'-5')-5'-thio-5'-deoxythymidine?

You can request a quote for Thymidylyl(3'-5')-5'-thio-5'-deoxythymidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Thymidylyl(3'-5')-5'-thio-5'-deoxythymidine?

Yes, KEHONG BIO provides custom synthesis services for Thymidylyl(3'-5')-5'-thio-5'-deoxythymidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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